Virtual screening reveals aprepitant to be a potent inhibitor of neutral sphingomyelinase 2: implications in blockade of exosome release in cancer therapy [PDF]
, 2023 Milad Moloudizargari +5 more
openalex +1 more source
Scottish and Newcastle antiemetic pre-treatment for paracetamol poisoning study (SNAP) [PDF]
, 2013 BACKGROUND: Paracetamol (acetaminophen) poisoning remains the commonest cause of acute liver injury in Europe and North America. The intravenous (IV) N-acetylcysteine (NAC) regimen introduced in the 1970s has continued effectively unchanged.
A Markham +29 more
core +1 more source
Cytotoxic and apoptotic effects of neurokinin-1 receptor (NK1R) antagonist on multiple myeloma cells [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2019 Background and Aim: Despite therapeutic improvements in recent decades, multiple myeloma (MM) still remains as one of the leading causes of death all over the world. Previous studies have indicated role of neurokinin-1 receptor (NK1R) in the pathogenesis
Elham Razani, Davood Bashash
doaj +1 more source
PENGARUH PENGGUNAAN BAHAN PENGHANCUR AMILUM MANIHOT TERHADAP SIFAT FISIK TABLET EKSTRAK DAUN ALPUKAT (Persea americana Mill.) SECARA GRANULASI BASAH [PDF]
, 2010 Tanaman alpukat (Persea americana Mill.) merupakan salah satu tanaman obat tradisional yang mempunyai manfaat diantaranya sebagai obat batu ginjal. Daun Alpukat biasanya digunakan dalam bentuk rebusan yang dinilai kurang praktis sehingga perlu dibuat ...
GITARIA , MELIA RISKI
core
Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs [PDF]
, 2017 Gastrointestinal fluid is a complex milieu and it is recognised that gut drug solubility is different to that observed in simple aqueous buffers. Simulated gastrointestinal media have been developed covering fasted and fed states to facilitate in vitro ...
Dunn, Claire +4 more
core +1 more source
A Comparison of the Efficacy of 5 mg Olanzapine and Aprepitant in the Prevention of Multiple‐Day Cisplatin Chemotherapy‐Induced Nausea and Vomiting [PDF]
, 2022 Guang Liu +14 more
openalex +1 more source
Impact of 5-HT3 receptor antagonists on chemotherapy-induced nausea and vomiting: a retrospective cohort study [PDF]
, 2012 BACKGROUND: 1(st) generation 5-hydroxytryptamine receptor antagonists (5-HT(3) RAs), and palonosetron, a 2(nd) generation 5-HT(3) RA, are indicated for the prevention of chemotherapy (CT)-induced nausea and vomiting (CINV) associated with moderately (MEC)
David Cox +4 more
core +1 more source
Diabetic Gastroparesis: Functional/Morphologic Background, Diagnosis, and Treatment Options [PDF]
, 2005 The regulation of gastrointestinal motility mainly involves the smooth muscle, neural (extrinsic and intrinsic), and hormonal elements, the glial cells, and the interstitial cells of Cajal.
Horváth, Viktor József +4 more
core +2 more sources
Glucocorticoid receptor signalling activates YAP in breast cancer [PDF]
, 2017 The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo pathway leads to aberrant activation of the transcription co-activator YAP ...
Bertolio, Rebecca +12 more
core +3 more sources
Minimal renal toxicity after Rituximab DHAP with a modified cisplatin application scheme in patients with relapsed or refractory diffuse large B-cell lymphoma [PDF]
, 2016 Background: Rituximab (R) in combination with DHAP is a widely accepted salvage regimen for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL).
A. D. Ho +20 more
core +2 more sources