Results 81 to 90 of about 4,502 (202)
The Neurokinin-1 Receptor Antagonist Aprepitant: An Intelligent Bullet against Cancer?
Neurokinin-1 receptor (NK-1R) antagonists exert antitumor action, are safe and do not cause serious side-effects. These antagonists (via the NK-1R) exert multiple actions against cancer: antiproliferative and anti-Warburg effects and apoptotic, anti ...
Rafael Coveñas +3 more
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Cytotoxic and apoptotic effects of neurokinin-1 receptor (NK1R) antagonist on multiple myeloma cells [PDF]
Background and Aim: Despite therapeutic improvements in recent decades, multiple myeloma (MM) still remains as one of the leading causes of death all over the world. Previous studies have indicated role of neurokinin-1 receptor (NK1R) in the pathogenesis
Elham Razani, Davood Bashash
doaj +1 more source
The interaction of ifosfamide and aprepitant in gynecologic malignancies
•Aprepitant combined with ifosfamide may lead to encephalopathy.•Aprepitant-ifosfamide induced encephalopathy was of short duration in these cases.
Shindorf, Mackenzie L. +2 more
openaire +2 more sources
Aprepitant en el tratamiento de náusea y vómito inducidos por quimioterapia altamente emetogénica [PDF]
Se estudian 23 pacientes oncológicos, para comprobar la eficacia del "Aprepitant" encontrol de emesis provocada por administración de quimioterapia altamente emetogénica.
Duque Espinoza, Sandra +1 more
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Mechanism Underlying Conflicting Drug-Drug Interaction Between Aprepitant and Voriconazole via Cytochrome P450 3A4-Mediated Metabolism [PDF]
Background: Voriconazole is an antifungal drug for which therapeutic monitoring is recommended to prevent side effects. Temporary administration of the antiemetic drug fosaprepitant remarkably decreases the plasma concentration of voriconazole from the ...
Fujiyoshi,Masachika +12 more
core +1 more source
Xiao-nan Zhao,* Zhen-zi Bai,* Cheng-hua Li, Chuan-lun Sheng, Hong-yan Li Department of Infectious, The Third Hospital of Jilin University, Changchun City, Jilin Province 130033, People’s Republic of China*These authors contributed equally to this ...
Zhao X, Bai Z, Li C, Sheng C, Li H
doaj
Drug-drug interactions with aprepitant in antiemetic prophylaxis for chemotherapy
In the current guidelines to prevent hemotherapyinduced nausea and vomiting, multiple antiemetic drugs are administered simultaneously. In patients who receive highly emetogenic chemotherapy, aprepitant, an NK1-receptor antagonist, is combined with ...
Hoeven, J.J.M. van der +5 more
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Pharmacy residents have the opportunity to complete a research project during their residency training, which provides them with skills on how to conduct and manage a research project.
Koo, Alicia +5 more
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Pharmacy residents have the opportunity to complete a research project during their residency training, which provides them with skills on how to conduct and manage a research project.
Walker, Scott +5 more
core +1 more source
In-vitro und in-vivo Untersuchungen mit dem Antiemetikum Aprepitant
Aprepitant, ein Neurokinin-1-Rezeptorantagonist, wird zur Therapie des Zytostatika induzierten Erbrechen eingesetzt. Besonders hohe Wirksamkeit erzielt man gegen die verzögerte Emesis.
von Aretin, Marie-Bernadette
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