Results 91 to 100 of about 8,463 (257)

Efficacy and Safety of Conventional and Biologic Therapies in Prurigo Nodularis: A Systematic Review and Meta‐Analysis

International Journal of Dermatology, Volume 65, Issue 4, Page 724-736, April 2026.
ABSTRACT Prurigo nodularis (PN) is a chronic, intensely pruritic skin disorder characterized by hyperkeratotic nodules and a debilitating itch–scratch cycle. Conventional therapies have limited efficacy and safety issues, while biologics have recently emerged as a promising alternative.
Andrea Lancz, Fanni Adél Meznerics, Renáta Árok, Anna Sára Lengyel, Bence Szabó, Péter Hegyi, Norbert Kiss, András Bánvölgyi   +7 more
wiley   +1 more source

Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration [PDF]

, 2014
Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated ...
A Tidholm, BD Rose, CC Horn, CL Limebeer, DC Dale, DM Vail, E Portillo, EM Rock, G Jang, GK Ogilvie, GK Ogilvie, GP Chrousos, GR Morrow, H Imamura, Hannah Kenward, IK Vonderen van, J Ito, J Loor, JD Chen, Jonathan Elliott, K Barabas, K Olsson, KL Koch, L Kelland, LA Parker, LA Parker, Ludovic Pelligand, LX Cubeddu, LX Cubeddu, M Boer-Dennert de, M Fredrikson, M Minami, MK Samson, MS Kim, N Percie du Sert, N Percie du Sert, PL Andrews, PL Andrews, PL Andrews, RD Fisher, S Ina, S Robery, SD Caras, T Bloom, V Napadow, VA Puente-Redondo de la, X Yu   +46 more
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Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, Volume 65, Issue 4, Page 706-723, April 2026.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Alzheimer's disease (AD) and glioblastoma multiforme (GBM) are biologically distinct age‐related brain disorders with opposing clinical phenotypes. AD is characterised by progressive neurodegeneration and cognitive decline, whereas GBM is characterised by aggressive cellular proliferation and a poor prognosis.
Ana B. Caniceiro, Sofia P. Agostinho, Luiz F. Piochi, Nícia Rosário‐Ferreira, Irina S. Moreira   +4 more
wiley   +1 more source

A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research. [PDF]

, 2018
The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend.
Aapro, Aapro, Aapro, Ahmad, Alphin, Amin, Andrews, Andrews, Andrews, Andrews, Andrews, Andrews, Andrews, Angeli, Anttila, Appl, Armstrong, Ash, Atkinson, Axelsson, Babaoglu, Babkin, Baker, Bakker, Balaban, Barone, Batchelor, Benchaoui, Benchaoui, Bergeron, Bermudez, Bertaccini, Bertolini, Bhandari, Bhargava, Bianchi, Bignall, Birtley, Blair, Bockaert, Boisson, Booth, Borison, Borison, Borison, Borsook, Bountra, Boyd, Boyd, Boyle, Bradley, Brand, Brand, Briejer, Broad, Broad, Broad, Brogden, Brown, Bury, Bymaster, Camilleri, Camilleri, Carlsson, Carpenter, Carpenter, Cassidy, Cavella, Chakrabarti, Champion, Chandrasekharan, Chin, Chiu, Christie, Chu, Church, Clark, Clarke, Claude, Cooper, Coskun, Costall, Courvoisier, Crampton, Creytens, Currow, Danjoux, Darmani, Davis, de la Puente-Redondo, Diemunsch, Dietz, Dionne, Donovan, Douglas, Dumuis, Eglen, Emanuel, Ennis, Erspamer, Erspamer, Fairweather, Fangmann, Farmer, Faustini, Flaxman, Floczyk, Foubert, Fozard, Fozard, Fozard, Friend, Friend, Gaddum, Gardner, Gay, Gesztesi, Gibbs, Glaviano, Goddard, Golding, Golding, Gralla, Gralla, Greaves, Guttuso, Guttuso, Gylys, Gylys, Hale, Hamik, Harrington, Harris, Hasler, Hatcher, Hatcher, Hawthorn, Heckert, Helke, Henry, Herrstedt, Hesketh, Hill, Hill, Hocking, Holbrook, Holling, Holling, Holmes, Horn, Horn, Horn, Hornby, Hromatka, Huang, Huppert, Irwin, Isaacs, Ison, Jacoby, Janssen, Javid, Johnston, Jones, Jordan, Justin-Besancon, Justin-Besancon, Kail, Kanba, Keating, Kebabian, Keiser, Kennis, Kenward, Kim, King, Kirchner, Koch, Koch, Kojima, Kramer, Kranke, Kris, Kroeze, Kubo, Kundu, Lackner, Laird, Lal, Lang, Lau, Lau, Lee, Lees-Green, Leggio, Lembo, Lembo, Lentz, Lewis, Limebeer, Liu, Lu, Lu, Lundberg, López-Muñoz, Maceira, MacIntosh, Maggi, Markey, Marrinan, McEachern, McFarlane, McLean, McRitchie, Meek, Meltzer, Midani, Millan, Miller, Minami, Miner, Miner, Miner, Minton, Moertel, Money, Moreland, Moyer, Muchatuta, Napadow, Navari, Navari, Newton, Ng, Noble, Norton, O'Grady, Oman, Ortiz, Owens, Owyang, Palazzo, Parker, Parkinson, Pasricha, Peeters, Penta, Percie du Sert, Percie du Sert, Peroutka, Peroutka, Pickel, Pinder, Plezia, Prakash, Profet, Profet, Reason, Reason, Reavley, Reinhardt, Rennie, Revicki, Rhee, Rich, Ritter, Robinson, Rock, Rojas, Rojas, Rojas, Rosenfeld, Rupniak, Sallen, Saller, Sam, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Sanger, Saria, Sawhney, Schmidt, Schulze-Delrieu, Schurig, Sclocco, Sigwald, Simoneau, Simons, Sirven, Slater, Smith, Smith, Sneader, Snider, Snyder, Soergel, Soto, Soukop, Spinks, Srivastava, Stadler, Stefanini, Stern, Stern, Stoltz, Sugino, Takatani, Tattersall, Tattersall, Thearle, Tonato, Tremblay, Tsuji, Tu, Ueno, Ueno, Vail, Van Sickle, Vincent, von Euler, von Euler, Wampler, Wang, Wang, Wang, Warr, Warr, Watson, Watson, Weerts, Weigel, Whitwam, Wong, Wyant, Yates, Zhong   +349 more
core   +3 more sources

Avoidant‐Restrictive Food Intake Disorder Is Common in Adults With Cyclic Vomiting Syndrome and Is Associated With Malnutrition

Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.
One in three adults with CVS were found to have a positive screen for ARFID. Most patients at risk of ARFID (NIAS+) had evidence of malnutrition and micronutrient deficiency. We recommend routine screening of patients with CVS for ARFID and referral to a registered dietitian to optimize clinical outcomes. ABSTRACT Background In cyclic vomiting syndrome
Thangam Venkatesan, Praveen S. Goday, Saranya Arumugam, Kebire Gofar, Mahima Vyas, Ana Petrova, Raul Jimenez‐Castillo, Muhammad Ayyan, Sonali Srivastava, Kristen Heitman, Peter Madril, Kristin Goheen, Kristen M. Roberts   +12 more
wiley   +1 more source

Adherence to ESMO clinical recommendations for prophylaxis of chemotherapy-induced nausea and vomiting [PDF]

, 2018
Background: We assessed adherence to the European Society of Medical Oncology (ESMO)/Multinational Association of Supportive Care in Cancer recommendations for prophylaxis of chemotherapy-induced nausea and vomiting (CINV) at our institution.
Aebi, Stefan, Burmeister, Henning, Fey, Martin, Gautschi, Oliver, Studer, Cristina   +4 more
core  

Detection of an Antagonist Bound to the Neurokinin a Receptor in Styrene–Maleic Acid Lipid Particles by 19F Ultrafast Magic‐Angle Spinning Nuclear Magnetic Resonance Spectroscopy

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
The detection of a fluorinated antagonist bound to the neurokinin A receptor by 19F ultrafast MAS NMR is demonstrated. Therefore, the receptor is purified by detergent‐free extraction by styrene maleic acid copolymer encapsulation and subsequently characterised.
Samuel Seidl, Aditya Prasad Patra, Chengkang Li, Johanna Becker‐Baldus, Stefanie Kaiser, Christoph Reinhart, Clemens Glaubitz   +6 more
wiley   +1 more source

Herbal medicines for the treatment of cancer chemotherapy-induced side effects [PDF]

, 2015
Accumulating evidence suggests that Japanese herbal medicines, called Kampo, have beneficial effects on cancer chemotherapy-induced side effects. Rikkunshito ameliorates cisplatin-induced anorexia through an antagonistic effect on the 5-HT receptors and ...
Hiroshi Takeda, Shunsuke Ohnishi
core   +2 more sources

PENGARUH PENGGUNAAN BAHAN PENGHANCUR AMILUM MANIHOT TERHADAP SIFAT FISIK TABLET EKSTRAK DAUN ALPUKAT (Persea americana Mill.) SECARA GRANULASI BASAH [PDF]

, 2010
Tanaman alpukat (Persea americana Mill.) merupakan salah satu tanaman obat tradisional yang mempunyai manfaat diantaranya sebagai obat batu ginjal. Daun Alpukat biasanya digunakan dalam bentuk rebusan yang dinilai kurang praktis sehingga perlu dibuat ...
GITARIA , MELIA RISKI
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