Results 91 to 100 of about 4,502 (202)

Is Aprepitant Effective in Preventing Postoperative Nausea and Vomiting?

, 2016
OBJECTIVE: The objective of this selective EBM review is to determine whether or not aprepitant is effective in preventing postoperative nausea and vomiting.
Gomberg, Rebeccah M.
core  

Effect of Aprepitant in Patient with Gastroparesis and Related Disorders

, 2018
Article: Aprepitant Has Mixed Effects on Nausea and Reduces Other Symptoms in Patients with Gastroparesis and Related ...
Moo In Park, Kyoungwon Jung
core   +1 more source

Efficacy of Aprepitant for Nausea in Patients with Head and Neck Cancer Receiving Daily Cisplatin Therapy

, 2014
Background: Although efficacy of aprepitant for suppressing emesis associated with single-dose cisplatin has been demonstrated, there are limited data on the antiemetic effect of this oral neurokinin-1 receptor antagonist during daily administration of ...
Kaneko, Kenichi, Takano, Atsushi, Katsura, Motoyasu, Takahashi, Haruo, Yamaguchi, Nimpei, Ishimaru, Kotaro   +5 more
core   +1 more source

Cost-Effectiveness of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting Associated with Highly Emetogenic Chemotherapy

, 2007
ObjectivesChemotherapy-induced nausea and vomiting (CINV) is a significant problem for cancer patients. Aprepitant, a novel NK-1 receptor antagonist, is approved for use with 5-HT3 antagonists and corticosteroids to prevent CINV associated with highly ...
Flowers, Christopher, Wojtanowski, Steven, Tumeh, John, Moore, Susan   +3 more
core   +1 more source

Antipruritic vs. Antitumour Action of Aprepitant: A Question of Dose

, 2019
A recently published study of 8 patients with cutaneous T-cell lymphomas (CTCL) treated with aprepitant (1) reported that the neurokinin-1 receptor (NK-1R) antago-nist aprepitant did not completely modify CTCL disease activity. The authors concluded that
Rafael Coveñas, Miguel Muñoz, Coveñas, Rafael, Parrilla, Julio, Marisa Rosso, Muñoz, Miguel, Julio Parrilla, Rosso, Marisa   +7 more
core   +1 more source

Antitumor Strategies Targeting Peptidergic Systems

Encyclopedia
Peptidergic systems show promise as targets for fighting tumors. While some peptides encourage the growth and spread of tumor cells and angiogenic mechanisms, others display antitumor properties. As such, peptide ligands and receptor antagonists could be
Francisco D. Rodríguez, Rafael Coveñas
doaj   +1 more source

Combined neurokinin-1 receptor antagonist and sorafenib is a promising approach for hepatocellular carcinoma therapy

Egyptian Liver Journal
Background HCC (Hepatocellular carcinoma) is the most common primary malignant cancer in the liver. Treatment options to incurable HCC such as sorafenib, an oral multikinase inhibitor, had numerous side effects and questionable effectiveness.
Heba E. Sedky, Yasmine N. Elwany, Eman S. El Alfy, Mona N. Elwany, Yasmin M. Nabil, Hazem F. Manna, Mohamed A. Abdelaziz, Wessam F. El Hadidy   +7 more
doaj   +1 more source

The efficacy of combination of ondansetron and aprepitant on preventing the radiotherapy-induced nausea and vomiting

Journal of Research in Medical Sciences, 2015
Background: Depending on the site of irradiation, about 40-80% of patients undergoing radiotherapy (RT) will experience nausea and/or vomiting. The current study aimed to investigate the efficacy of ondansetronas as a single agent and with a combination ...
Hamid Emami, Simin Hematti, Seyed Masoud Saeidian, Awat Feizi, Shahin Taheri, Pourya Adeli, Golshan Mahmoudi   +6 more
doaj  

Efficacy of Aprepitant and Ondansetron in Managing Postoperative Nausea and Vomiting in Perioperative Obese Patients

Purpose/Background Postoperative nausea and vomiting (PONV) is a common adverse event that occurs during the recovery period following anesthesia. PONV has been reported to affect nearly 80% of patients, leading to prolonged hospitalization, increases in
Revon, Reagan, Stewart, Jada, Castellaw, Samantha, Roberts, Ashlee, Reed, Laura, DNP, FNP-BC, Belflower, Bobby, DNSc, NNP-BC, FAANP, Accardo, Dwayne, DNP, CRNA, FAANA   +6 more
core   +1 more source

Perioperative Administration of Emend® (Aprepitant) at a Tertiary Care Children’s Hospital: A 12-Month Survey

Clinical Pharmacology: Advances and Applications, 2019
Anuradha Kanaparthi,1 Sarah Kukura,2 Natalie Slenkovich,2 Faris AlGhamdi,2 Shabana Z Shafy,2 Mohammed Hakim,2 Joseph D Tobias2,3 1College of Medicine, Northeast Ohio Medical University (NEOMED), Rootstown, Ohio, USA; 2Department of Anesthesiology & ...
Kanaparthi A, Kukura S, Slenkovich N, AlGhamdi F, Shafy SZ, Hakim M, Tobias JD   +6 more
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