Results 101 to 110 of about 110,212 (273)

Efficacy and safety of antifibrinolytic agents in spinal surgery: a network meta-analysis

Chinese Medical Journal, 2019
. Background:. Significant blood loss is still one of the most frequent complications in spinal surgery, which often necessitates blood transfusion. Massive perioperative blood loss and blood transfusion can create additional risks. Aprotinin, tranexamic
Lei Yuan, Yan Zeng, Zhong-Qiang Chen, Xin-Ling Zhang, Shuo Mai, Pan Song, Li-Yuan Tao, Qiang Shi   +7 more
doaj   +1 more source

Aprotinin use in thoracic aortic surgery: Safety and outcomes [PDF]

, 2006
Artyom Sedrakyan, Albert W. Wu, George Sedrakyan, Marie Diener‐West, Maryann Tranquilli, John A. Elefteriades   +5 more
openalex   +1 more source

Zinc‐Mediated Lysosomal Destabilization Links Mitochondrial Damage to Neuronal Death in a Cellular MPP+ Model of Parkinson's Disease

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
When mitochondria are damaged by MPP+, they produce excess reactive oxygen species (ROS) and release zinc (Zn2+) inside the cell. This surge in zinc overwhelms lysosomes—the cell's major zinc‐buffering organelles—causing their membranes to break down. Leaking lysosomal enzymes then trigger neuronal death. Treatments that reduce ROS, bind zinc, or block
Hyun‐Seung Lee, Sun‐Ah Kang, Jae‐Won Eom, Min Seong Kim, Ji‐Soo Kim, Yang‐Hee Kim   +5 more
wiley   +1 more source

Hemochron vs. Hemotec Kaolin ACT Comparison with Aprotinin Use in Congenital Heart Surgery [PDF]

, 1996
Jodie M. Ecklund, Mary M. McCall, Richard Southworth, Mindy M. Blackwell, Jeffrey B. Riley   +4 more
openalex   +1 more source

Aprotinin—Drug against Respiratory Diseases [PDF]

, 2023
Alexandre V. Ivachtchenko, Andrey A. Ivashchenko, Dmitrii O. Shkil, Ilya A. Ivashchenko   +3 more
openalex   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

The use of fibrinolysis inhibitors in cardiac surgery with cardiopulmonary bypass (literature review)

Вестник анестезиологии и реаниматологии
In cardiac surgery with cardiopulmonary bypass (CPB) is a common complication. The incidence of this complication in cardiac surgery patients is estimated at about 10%.
V. Yu. Medvedeva, K. N. Khrapov, A. A. Khryapa, K. Yu. Kankova   +3 more
doaj   +1 more source

Aprotinin in aortic surgery requiring profound hypothermia and circulatory arrest [PDF]

, 1997
S Rooney
openalex   +1 more source

Reduction of acute haemorrhage with aprotinin [PDF]

, 1993
S. Valentine, Paula Williamson, Debbie Sutton   +2 more
openalex   +1 more source

Inhibition of Intrinsic Thrombin Generation

Drug Target Insights, 2006
Background: The contact phase of coagulation is of physiologic/pathophysiologic importance, whenever unphysiologic polynegative substances such as cell fragments (microparticles) get in contact with blood.
Thomas W. Stief
doaj