Results 101 to 110 of about 114,758 (340)

A lymphoma plasma membrane-associated protein with ankyrin-like properties. [PDF]

open access: yes, 1986
In this study we have used several complementary techniques to isolate and characterize a 72-kD polypeptide that is tightly associated with a major mouse T-lymphoma membrane glycoprotein, gp 85 (a wheat germ agglutinin-binding protein), in a 16 S complex.
Balazovich, K   +3 more
core  

Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis

open access: yesCritical Care, 2010
IntroductionAntifibrinolytic agents are commonly used during cardiac surgery to minimize bleeding. Because of safety concerns, aprotinin was withdrawn from the market in 2007. Since then, tranexamic acid (TXA) has become the antifibrinolytic treatment of
M. Sander   +5 more
semanticscholar   +1 more source

Allosteric modulation of protein kinase A in individuals affected by NLPD‐PKA, a neurodegenerative disease in which the PRKAR1B L50R variant is expressed

open access: yesThe FEBS Journal, EarlyView.
In healthy neurons, Protein kinase A (PKA) forms a tetrameric holoenzyme enabling precise allosteric regulation. We characterized a novel neurodegenerative disease, neuronal loss, and parkinsonism driven by PRKAR1B mutation (NLPD‐PKA), demonstrating disrupted holoenzyme assembly, reduced cooperativity, and increased catalytic subunit nuclear ...
Tal Benjamin‐Zukerman   +13 more
wiley   +1 more source

Correction of the Fibrinolytic Type of the Disseminated Intravascular Coagulation Syndrome in the Early Postoperative Period

open access: yesОбщая реаниматология, 2007
Objective: to comparatively evaluate the efficiency and safety of trasylol and aprotex used in the treatment of the fibrinolytic type of disseminated intravascular coagulation (DIC) syndrome after long abdominal operations.Materials and methods.
S. V. Sinkov   +3 more
doaj   +1 more source

Aprotinin reduces blood loss in off-pump coronary artery bypass (OPCAB) surgery [PDF]

open access: yes, 2017
Objective: Effects of aprotinin in off-pump coronary artery bypass (OPCAB) surgery have not yet been described. This study analyses hemostasiologic changes and potential benefit in OPCAB patients treated with aprotinin.
Berdat, P.A.   +5 more
core  

Translation inhibition by rocaglates is independent of eIF4E phosphorylation status [PDF]

open access: yes, 2016
Rocaglates are natural products that inhibit protein synthesis in eukaryotes and exhibit antineoplastic activity. In vitro biochemical assays, affinity chromatography experiments coupled with mass spectrometry analysis, and in vivo genetic screens have ...
Cencic, Regina   +4 more
core   +1 more source

Cadherin‐6 controls neuronal migration during mouse neocortical development via an integrin‐mediated pathway

open access: yesThe FEBS Journal, EarlyView.
Neuronal migration plays essential roles in the establishment of mammalian brains, and its impairment causes severe developmental abnormalities and behavioral and cognitive deficits. Here, we report that cadherin‐6 (CDH6), an unusual cadherin molecule containing an RGD integrin‐binding motif in the first extracellular domain, controls the motility of ...
Yuki Hirota   +7 more
wiley   +1 more source

Defining the interactome of the pancreas‐specific SPCA2 isoform (SPCA2C) identifies unique links to store‐operated Ca2+ entry

open access: yesThe FEBS Journal, EarlyView.
A BioID screen identified interacting proteins for secretory pathway calcium (Ca2+) ATPase 2C (SPCA2C) and showed new links to store‐operated Ca2+ entry. Interactions between SPCA2C and Orai1 were confirmed, along with newly identified interactions with STIM1 and CCDC47.
Petra Samardzija   +9 more
wiley   +1 more source

Aprotinin revisited [PDF]

open access: yesIntensive Care Medicine, 2013
Stacia M. DeSantis, Christos Lazaridis
openaire   +2 more sources

Anti-tumour Activity of Aprotinin [PDF]

open access: green, 1974
A.L. Latner, E. Longstaff, G. A. Turner
openalex   +1 more source

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