Results 81 to 90 of about 75,167 (214)

Protective effects of the antioxidant Ginkgo biloba extract and the protease inhibitor aprotinin against Leiurus quinquestriatus venom-induced tissue damage in rats

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
Oxidative stress and proteases have been implicated in several diseases and extensive evidence indicates that antioxidants and protease inhibitors help prevent organ functional damage. Leiurus quinquestriatus (LQQ) scorpion venom causes cellular injuries
A. J. Fatani, H. A. Al-Zuhair, H. I. Yaquob, A. A. Abdel-Fattah, M. I. El-Sayed, F. A. El-Sayed   +5 more
doaj   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Aprotinin recovery: comparison between biospecific and pseudobiospecific affinity adsorptions

, 2015
Two adsorption techniques were studied as potential methods for the recovery of aprotinin: a biospecific adsorption (using immobilized trypsin and chymotrypsin as ligants) and a pseudobiospecific adsorption of aprotinin-trypsin complex onto IMAC matrix ...
Miranda, EA, MIRANDA, E. A., Vijayalakshmi, MA, Azzoni, AR, Tamagawa, RE, AZZONI, A. R., TAMAGAWA, R. E., VIJAYALAKSHMI, M. A.   +7 more
core   +1 more source

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source

Isolierung und Charakterisierung von Aprotinin und Aprotinin-Isoinhibitoren aus Rinderlungen

, 1987
Siekmann J. Isolierung und Charakterisierung von Aprotinin und Aprotinin-Isoinhibitoren aus Rinderlungen.
Siekmann, Jürgen
core  

Analyses of coronary graft patency after aprotinin use: Results from the International Multicenter Aprotinin Graft Patency Experience (IMAGE) trial

, 1998
Objective: We examined the effects of aprotinin on graft patency, prevalence of myocardial infarction, and blood loss in patients undergoing primary coronary surgery with cardiopulmonary bypass.
Griepp, R. B., Uretzky, G., Pettersson, G., Bidstrup, B., Westaby, S., Alderman, E. L., Rich, J. B., Hantler, C. B., Nadel, A., Vidne, B., Thiis, J. J., Chaitman, B., Nili, M., Schaff, H., Levy, J. H.   +14 more
core   +1 more source

Aprotinin revisited [PDF]

Intensive Care Medicine, 2013
Stacia M, DeSantis, Christos, Lazaridis
openaire   +2 more sources

Irradiation‐Induced CD62L Shedding in Human Plasmacytoid Dendritic Cells Depends on ADAM17 and p38 MAPK

Immunology, Volume 179, Issue 4, Page 671-681, December 2026.
Human plasmacytoid dendritic cell‐based vaccines efficiently migrate from blood to lymph nodes and prime naive T cells in humanised mice. Irradiation‐induced CD62L shedding, mediated by p38 MAP kinase and ADAM17, is involved in the regulation of PDC migration to secondary lymphoid organs in this model.
Estelle Leplus, Jamila Kacher, Dalil Hannani, Guillaume Vayssiere, Jean‐Paul Molens, Karine Laulanier, Dan Georgess, Véronique Josserand, Philippe Saas, Séverine Planel, Laurence Chaperot, Joel Plumas   +11 more
wiley   +1 more source

Avaliação da aprotinina na redução da resposta inflamatória sistêmica em crianças operadas com circulação extracorpórea Assessment of aprotinin in the reduction of inflammatory systemic response in children undergoing surgery with cardiopulmonary bypass

Brazilian Journal of Cardiovascular Surgery, 2010
OBJETIVO: Avaliar se a aprotinina em altas doses hemostáticas pode reduzir o processo inflamatório após circulação extracorpórea (CEC) em crianças. MÉTODOS: Estudo prospectivo randomizado em crianças de 30 dias a 4 anos de idade, submetidas à correção de
Cesar Augusto Ferreira, Walter Villela de Andrade Vicente, Paulo Roberto Barbosa Evora, Alfredo José Rodrigues, Jyrson Guilherme Klamt, Ana Paula de Carvalho Panzeli Carlotti, Fábio Carmona, Paulo Henrique Manso   +7 more
doaj   +1 more source

TMEM55B Maintains Lysosomal Homeostasis and Promotes ER–Lysosome Calcium Signaling

Traffic, Volume 27, Issue 4, December 2026.
Hypothetical model: The lysosomal protein TMEM55B interacts with an ER protein complex containing Protrudin and PDZD8 at ER–lysosome membrane contact sites, and also acts to stabilize v‐ATPase in lysosomes. Through these interactions, TMEM55B contributes to the maintenance of luminal homeostasis, including lysosomal acidification and regulates ER ...
Nagi Mukae, Honoka Maki, Michiko Shirane
wiley   +1 more source