Results 101 to 110 of about 74,076 (196)
Isolierung und Charakterisierung von Aprotinin und Aprotinin-Isoinhibitoren aus Rinderlungen
, 1987 Siekmann J. Isolierung und Charakterisierung von Aprotinin und Aprotinin-Isoinhibitoren aus Rinderlungen.
Siekmann, Jürgen
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Postprandial Glucagon Action in the Human Brain
Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5926-5938, July 2026.ABSTRACT Aims Elevated fasting glucagon is linked to hyperglycemia, but postprandial glucagon effects are less understood. Recent evidence suggests metabolic benefits of rising glucagon after oral glucose intake, potentially impacting brain‐mediated whole‐body metabolism.
Robert Wagner +11 more
wiley +1 more source
Inhibition of Intrinsic Thrombin Generation
Drug Target Insights, 2006 Background: The contact phase of coagulation is of physiologic/pathophysiologic importance, whenever unphysiologic polynegative substances such as cell fragments (microparticles) get in contact with blood.
Thomas W. Stief
doaj
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.Under normal conditions, RagD and mTORC1 respond to amino acid changes. Upon stimulation, active mTORC1 phosphorylates S6K, 4E‐BP1, and TFEB. In response to starvation, mTORC1 is inactive. Our data indicate that the RRAGD p.(Ser76Leu) variant maintains the phosphorylation of mTORC1 targets during starvation in T‐REx HeLa cells.
Anastasia Adella +11 more
wiley +1 more source
Vasoactive effects of aprotinin
, 1992 The protease inhibitor aprotinin was given a) in experimental septic shock, and b) in patients with hepatic cirrhosis and ascites, since in both conditions, activation of the plasma kallikrein-kinin system is associated with pathological systemic ...
Cumming, A. D. +4 more
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Augmentation by aprotinin of the renal response to vasopressin
, 1987 Augmentation by aprotinin of the renal response to vasopressin. We contrasted the renal effects of vasopressin in Brattleboro rats with and without pretreatment with aprotinin (20,000 KIU kg-1).
Baer, Philip G. +2 more
core +1 more source
S100A4 Orchestrates Fibroblast Fate to Drive Fibrotic Remodeling
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.Fibrotic stimuli induce S100A4 expression, promoting the activation of apoptosis‐resistant fibroblasts through engagement of ERK‐associated signaling. In fibroblasts, S100A4 orchestrates fibroblast fate by enhancing migration, promoting stress fiber formation, increasing ECM contractility, upregulating α‐SMA expression, and supporting survival ...
Spring Li +6 more
wiley +1 more source
947-113 Aprotinin Produces Ion Channels in lipid Bilayers
, 1995 Aprotinin, a 58 Amino Acid peptide protease inhibitor, is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. Its mechanism of action is unknown.
Titov, Siava +2 more
core +1 more source
Aprotinin and its target enzymes in vitro and in vivo [PDF]
, 1990 Hoffmeister, H. +3 more
core +1 more source
Effect of aprotinin on vascular reactivity of coronary bypass grafts
, 1997 Objective: Aprotinin reduces postoperative bleeding and the need for transfusion after cardiopulmonary bypass. The current clinical concern about aprotinin is that it may increase the incidence of postoperative graft thrombosis and thromboembolic ...
Allen, Sean +4 more
core +1 more source