Results 101 to 110 of about 75,167 (214)

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, Volume 293, Issue 21, Page 6323-6348, November 2026.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

The effects of aprotinin on thromboelastography with three different activators

open access: yes, 2001
Background: Thromboelastography is used for assessment of hemostasis. Adherence to thromboelastography-guided algorithms and aprotinin administration each decrease bleeding and blood product usage after cardiac surgery.
Avidan, M S   +5 more
core   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

open access: yesJournal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon   +12 more
wiley   +1 more source

Acute Respiratory Distress Syndrome after Aprotinin Infusion

open access: yes, 1997
Objective To report a case of acute respiratory distress syndrome (ARDS) following first exposure to aprotinin. Case Summary A 24-year-old previously healthy white man was treated with aprotinin infusion because of bleeding following tonsillectomy.
Zeljko Vucicevic, Tomislav Suskovic
core   +1 more source

APROTININ EFFECT ON PLATELET-FUNCTION AND CLOTTING DURING CARDIOPULMONARY BYPASS

open access: yes, 1994
A variety of studies have been performed on the preservation of hemostasis by aprotinin during cardiopulmonary bypass (CPB). It appears that the mechanism of aprotinin to preserve hemostasis can be interpreted in different ways.
BOONSTRA, PW   +4 more
core   +1 more source

High‐variance phenome database reveals important roles of WD40 proteins in the plant pathogenic fungus Fusarium graminearum

open access: yesNew Phytologist, Volume 252, Issue 3, Page 1215-1231, November 2026.
Functional analysis of predicted interaction‐associated WD40 blades in Fgwd101 and Fgwd048 of Fusarium graminearum. Summary WD40 is a highly conserved protein domain in eukaryotes that functions as a versatile platform for protein–protein interactions and participates in diverse biological processes.
Soyoung Choi   +15 more
wiley   +1 more source

Inhibition of Intrinsic Thrombin Generation

open access: yesDrug Target Insights, 2006
Background: The contact phase of coagulation is of physiologic/pathophysiologic importance, whenever unphysiologic polynegative substances such as cell fragments (microparticles) get in contact with blood.
Thomas W. Stief
doaj  

The use of fibrinolysis inhibitors in cardiac surgery with cardiopulmonary bypass (literature review)

open access: yesВестник анестезиологии и реаниматологии
In cardiac surgery with cardiopulmonary bypass (CPB) is a common complication. The incidence of this complication in cardiac surgery patients is estimated at about 10%.
V. Yu. Medvedeva   +3 more
doaj   +1 more source

Searching for Novel COVID19 Treatments: Towards Covalent TMPRSS2 Inhibitors

open access: yesChemMedChem, Volume 21, Issue 19, 14 October 2026.
We designed, synthesised, and evaluated new guanidine derivatives as potential covalent inhibitors of TMPRSS2, a key protease for SARS‐CoV‐2 entry. Computational studies showed that some compounds have improved binding over nafamostat. However, experimentally none effectively blocked viral entry in cell assays, indicating further optimisation is needed.
Marco Minneci   +6 more
wiley   +1 more source

Aprotinin steril szűrésének megoldása

open access: yes, 2020
Az aprotinin szűrésének technológiai transzfere 'C' minősítésű térből aszeptikus körülmények közéVegyészmérnökBSc ...
Sebők, Annamária
core  

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