Results 71 to 80 of about 114,163 (306)
Вестник анестезиологии и реаниматологииThe objective was to compare the efficacy and safety of the use of aprotinin and tranexamic acid in cardiac surgery with cardiopulmonary bypass (CPB) in adult patients.Materials and methods. A randomized prospective comparative study was conducted.
V. Yu. Medvedeva +7 more
doaj +1 more source
Effect of Intraduodenal Bile and Na-Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Secretin, Pancreatic Polypeptide, and Gastrin in Man [PDF]
, 1990 The effect of intraduodenally administered cattle bile (CB) and Na-taurodeoxycholate (TDC) on basal pancreatic secretion and plasma levels of secretin, pancreatic polypeptide (PP), and gastrin were investigated on two separate days in 10 fasting ...
A. Scharl +46 more
core +1 more source
Journal of Thoracic and Cardiovascular Surgery, 2012 OBJECTIVE Factors contributing to postoperative complications include blood loss and a heightened inflammatory response. The objective of this study was to test the hypothesis that aprotinin would decrease perioperative blood product use, reduce ...
E. Graham +10 more
semanticscholar +1 more source
The FEBS Journal, EarlyView.NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu +9 more
wiley +1 more source
The FEBS Journal, EarlyView.Ulvan is a polysaccharide available from green seaweed with beneficial properties for various applications. The full potential of ulvan requires enzymatic degradation of the polymer, thus producing ulvan oligosaccharides. This study expands the armoury of characterised ulvan lyases.
Andrius Jasilionis +8 more
wiley +1 more source
Topical Use of Aprotinin in Coronary Artery Bypass Surgery
Acta Medica, 1999 Objective: The internal mammary artery (IMA) ranks among excellent, widely used conduits for surgical coronary revascularization. Its harvesting and its using may cause other surgical and technical problems and complications and increase postoperative ...
Jiří Manďák +2 more
doaj +1 more source
Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization,secondary mediators, and Rac [PDF]
, 2010 The C-type lectin-like receptor 2 (CLEC-2)activates platelets through Src and Syk tyrosine kinases via a single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM).Here, we demonstrate using sucrose gradient ...
Alice Y. Pollitt +44 more
core +1 more source
The FEBS Journal, EarlyView.The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati +4 more
wiley +1 more source
The effect of aprotinin (trasylol) on postoperative bleeding in cyanotic congenital heart disease
The Turkish Journal of Pediatrics, 1991 Despite the widespread clinical success in open-heart surgery, bleeding after cardiopulmonary by-pass (CPB) has been a common problem especially in cyanotic congenital heart disease.
E Hazan +3 more
doaj
Antifibrinolytics in liver surgery
Indian Journal of Anaesthesia, 2010 Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures.
Jalpa Makwana +2 more
doaj +1 more source