Results 61 to 70 of about 44,465 (273)
The Effect of Aprotinin on Thrombelastography in Vitro [PDF]
Anaesthesia and Intensive Care, 1996 The effect of low dose (50 KIU/ml) and high dose (200 KIU/ml) aprotinin on standard thrombelastographic variables (r, K, α, MA) was examined in vitro using blood from forty ASA Class I patients. Both concentrations of aprotinin resulted in minor increases in r time above the normal range (P<0.05).
Neville M. Gibbs, George A. Chalkiadis
openaire +3 more sources
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source
Antifibrinolytics in liver surgery
Indian Journal of Anaesthesia, 2010 Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures.
Jalpa Makwana +2 more
doaj +1 more source
Monitoring activated clotting time for combined heparin and aprotinin application: in vivo evaluation of a new aprotinin-insensitive test using Sonoclot [PDF]
, 2017 Objective: Kaolin-based activated clotting time assessed by HEMOCHRON (HkACT) is a clinical standard for heparin monitoring alone and combined with aprotinin during cardiopulmonary bypass (CPB).
Furrer, Lukas +7 more
core
Risk factors for deterioration of renal function after coronary artery bypass grafting [PDF]
, 2010 Objective: Various definitions of impairment of renal function after coronary artery bypass grafting (CABG) are used in the literature. Depending on the definition, several risk factors are identified.
de Wolf, Andre +5 more
core +2 more sources
Aprotinin in severe acute pancreatitis
International Journal of Clinical Practice, 2010 Aprotinin, a Kunitz protease inhibitor, has a wide inhibitory action with particular activity against trypsin, chymotrypsin and kallikrein, making it theoretically attractive in ameliorating the effects of acute pancreatitis. Its use in acute pancreatitis has been studied for the last 50 years with disappointing results.
Beverley J. Hunt +2 more
openaire +2 more sources
Advanced Materials Technologies, EarlyView.Novel OoC platform with functional vascular networks highlights challenges in oxygenation. This study uses optical oxygen sensors to monitor oxygen during vascular formation, revealing perfusion limitations and highlighting the need for better oxygenation strategies.
Tarek Gensheimer +5 more
wiley +1 more source
Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery.
Journal of the American Medical Association (JAMA), 2007 CONTEXT Acute safety concerns have been raised recently regarding certain hemorrhage-sparing medications commonly used in cardiac surgery. However, no comprehensive data exist regarding their associations with long-term mortality. OBJECTIVE To contrast
D. Mangano +12 more
semanticscholar +1 more source
Is There a Surgical Role for Topical Aprotinin? [PDF]
Anesthesiology, 2008 To the Editor:—Two classes of intravenous drugs are commonly used in the perioperative setting to mitigate bleeding after cardiac surgery: lysine analogs (e.g., aminocaproic acid, tranexamic acid) and serine protease inhibitors (e.g., aprotinin).
Charles D. Collard +2 more
openaire +3 more sources
Advanced Materials Technologies, EarlyView.Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar +13 more
wiley +1 more source