Results 41 to 50 of about 75,167 (214)

SEMISYNTHESIS OF ARG-15-APROTININ, GLU-15-APROTININ, MET-15-APROTININ, AND NLE15-APROTININ INVOLVING ENZYMATIC PEPTIDE-BOND RESYNTHESIS

, 1989
BECKMANN J, MEHLICH A, SCHRODER W, Wenzel H, Tschesche H. SEMISYNTHESIS OF ARG-15-APROTININ, GLU-15-APROTININ, MET-15-APROTININ, AND NLE15-APROTININ INVOLVING ENZYMATIC PEPTIDE-BOND RESYNTHESIS. JOURNAL OF PROTEIN CHEMISTRY.
MEHLICH, A, SCHRODER, W, Wenzel, Herbert, Armin Mehlich, Herbert R. Wenzel, Tschesche, Harald, Harald Tschesche, Werner Schröder, BECKMANN, J, Jürgen Beckmann   +9 more
core   +1 more source

Self-Assembled Mucin-Containing Microcarriers via Hard Templating on CaCO3 Crystals

Micromachines, 2018
Porous vaterite crystals of CaCO3 are extensively used for the fabrication of self-assembled polymer-based microparticles (capsules, beads, etc.) utilized for drug delivery and controlled release.
Nadezhda G. Balabushevich, Ekaterina A. Sholina, Elena V. Mikhalchik, Lyubov Y. Filatova, Anna S. Vikulina, Dmitry Volodkin   +5 more
doaj   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Dekortikasyon ameliyatlarında aprotinin kullanımı [PDF]

, 1994
Selçuk Üniversitesi Tıp Fakültesi Göğüs Kalp Damar Cerrahisi Kliniği'nde dekortikasyon ameliyatı yapılan 40 hasta per ve postoperatif değerlendirmeye tabi tutulmuş olup, 20 hastaya aprotinin uygulanmış olup, postoperatif drenlerden olan kanama miktarı ...
Sunam, Güven Sadi
core   +2 more sources

Aprotinin Dosing: How Much Is Enough?

, 2023
Coagulopathy and postoperative bleeding continue to be a major concern for patients undergoing cardiac surgery with cardiopulmonary bypass. Pharmacologic attenuation of this morbidity has been one area that clinicians have held in high interest ...
Kevin S. Niimi
core   +1 more source

Pathogenetic treatment of influenza patients with aerosolized form of aprotinin, a protease inhibitor

Биопрепараты: Профилактика, диагностика, лечение, 2018
Therapeutic and antiviral efficacies of inhalations of aerosolized aprotinin, a protease inhibitor, which blocks a stage of influenza virus proteolytic activation, were studied.
O. P. Zhirnov, N. O. Bokova, E. I. Isaeva, I. V. Vorobieva, N. A. Malyshev   +4 more
doaj  

Aprotinina preserva plaquetas em crianças com cardiopatia congênita acianogênica operadas com circulação extracorpórea? Does aprotinin preserve platelets in children with acyanogenic congenital heart disease undergone surgery with cardiopulmonary bypass?

Brazilian Journal of Cardiovascular Surgery, 2009
OBJETIVO: Avaliação dos efeitos hemostáticos e plaquetários em crianças submetidas a correção de cardiopatias congênitas acianogênicas com circulação extracorpórea que receberam aprotinina. MÉTODOS: Estudo prospectivo randomizado em crianças de 30 dias a
Cesar Augusto Ferreira, Walter Villela de Andrade Vicente, Paulo Roberto Barbosa Évora, Alfredo José Rodrigues, Jyrson Guilherme Klamt, Ana Paula de Carvalho Panzeli Carlotti, Fábio Carmona, Paulo Henrique Manso   +7 more
doaj   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

The effect of two different doses of aprotinin on hemostasis in cardiopulmonary bypass surgery: similar transfusion requirements and blood loss

Haematologica, 2000
BACKGROUND AND OBJECTIVES: Various dosages of aprotinin have proven to be effective in reducing blood loss and allogeneic transfusion requirements in cardiopulmonary bypass surgery, despite the controversy surrounding the precise hemostatic mechanisms of
A Santamaria, J Mateo, A Oliver, H Litvan, J Murillo, JC Souto, J Fontcuberta   +6 more
doaj