Results 181 to 190 of about 68,358 (287)

Aptamer-Based Delivery of Genes and Drugs Across the Blood-Brain Barrier. [PDF]

Pharmaceuticals (Basel)
Yang L, Yin Y, Liu X, Guo B.
europepmc   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Scalable Multiparametric Characterization of Aptamer-Target Interactions. [PDF]

ACS Nano
Sulliger M, Peters M, Sottini A, Stuber A, Yang K, Nakatsuka N, Ortega Arroyo J, Quidant R.   +7 more
europepmc   +1 more source

Nanoparticles in microdroplets: Recent advances in microfluidic generators for producing functional microbeads

Droplet, EarlyView.
Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
  Bayinqiaoge, Chengchen Zhang, Shi‐Yang Tang   +2 more
wiley   +1 more source

Identification of a myosin 1B-binding aptamer for fluorescence imaging and targeted therapy of esophageal squamous cell carcinoma. [PDF]

Mater Today Bio
Wang Z, Xiao X, Zhang T, Li X, Ji M, Qian Y, Bai X, Li X, Lu J, Tang J, Liu K, Li Z, Yuan B.   +12 more
europepmc   +1 more source

Sheath‐assisted microfluidics for elasto‐inertial manipulation of micro/nanoparticles: From theory to biomedical applications

Droplet, EarlyView.
This review examines sheath‐assisted elasto‐inertial microfluidics, where viscoelastic and inertial forces synergize to manipulate particles. It analyzes the underlying mechanisms, system designs, and biomedical applications, proposing future research to advance high‐precision technologies.
Huan Wang, Yanting Wang, Yibo Cui, Limiao Yin, Jinwen Li, Yanxuan Wu, Piwu Li, Lei Zhao, Xiaowen Huang   +8 more
wiley   +1 more source

Development of an impedimetric aptasensor for Shiga-like toxin 1 using a DNA aptamer and an interdigitated microelectrode. [PDF]

RSC Adv
Mili M, Chinnadayyala SR, Cho S, Goswami P.   +3 more
europepmc   +1 more source

Electrode structures of solid–liquid interface‐based triboelectric nanogenerators and their applications

Droplet, EarlyView.
In this review, we have summarized the working principles and equivalent circuit diagrams of solid‐liquid interface triboelectric nanogenerators with different electrode structures, as well as the applications of devices with such structures in droplet mechanical energy harvesting and self‐powered sensing of liquid samples, along with their respective ...
Hanyue Liu, Man Zhang, Boyou Wang, Xiali Yang, Min Dai, Jing Pan, Qitao Zhou, Fan Xia   +7 more
wiley   +1 more source

Ribocentre-aptamer: an integrative, structure-focused database for RNA aptamers. [PDF]

Nucleic Acids Res
Lu Z, Sun H, Fu B, Ao Y, Wang J, Chen K, Luo Y, Li L, Qiu Z, Zhao J, Sun Y, Tan Z, Liu Q, Ren Y, Guo Z, Chen X, He Y, Zhao Y, Chen Y, Li M, Peng X, Huang B, Zhu S, Huang L, Miao Z.   +24 more
europepmc   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

Drug Testing and Analysis, EarlyView.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source