An AuNP-labeled triple-helix molecular switch for ultrasensitive, on-site detection of tetracycline in milk via fiber-optic localized surface plasmon resonance biosensing. [PDF]
Situ X, Li J, Zhang Y, Yan H.
europepmc +1 more source
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Molecularly Built Ligands Degrade Membrane Receptors via Enhancing Their Accumulation in Lysosomes
Dongchen Zhang +5 more
doaj +1 more source
Structure-guided development of an electrochemical aptasensor for Salmonella Typhi HlyE antigen detection using in silico and experimental approaches. [PDF]
Ahmad Najib M +11 more
europepmc +1 more source
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae +6 more
wiley +1 more source
Conjugated Polymers Engineered for Flexible/Stretchable Electronics
This review highlights glass transition temperature (Tg) as the central parameter linking molecular structure to device performance in conjugated polymers. By tuning backbone rigidity, side‐chain architecture, and dynamic bonding, Tg governs the balance between π–π stacking–enabled charge transport and mechanical compliance.
Yunchong Yang +5 more
wiley +1 more source
Intelligent nano‐platforms in breast cancer therapy: Current advances and future perspectives
The smart nano platform in breast cancer treatment is designed with advanced nanocarriers, including liposomes, hydrogels, porous nanoparticles, and aptamer‐based systems. These systems are capable of targeted drug release and response to environmental stimuli.
Tina Rahimi, Moluk Aivazi
wiley +1 more source
Allosteric ligand-aptamer complexes orchestrate supramolecular or transient catalytic, transcription and fibrinogenesis processes. [PDF]
Froim D +4 more
europepmc +1 more source
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin +3 more
wiley +1 more source
Complex interplay of riboregulatory mechanisms at the <i>gcvT</i>-NGFG_01513-<i>gcvH</i> operon of <i>Neisseria gonorrhoeae</i>. [PDF]
Bauer S, Rudel T, Beier D.
europepmc +1 more source

