Results 191 to 200 of about 29,754 (236)

Integrating Magnetic Bead-Based SELEX with <i>In Silico</i> Binding Analyses for the Identification of High-Affinity DNA Aptamers Targeting TAGLN2. [PDF]

ACS Omega
Martin DR, Waddad A, Gafar MA, Govender T, Cloete R, Madiehe AM, Meyer M.   +6 more
europepmc   +1 more source

High Sensitivity Cardiac Troponin I Detection via MP‐Locked Aptamer and Multimeric DNAzyme‐Coupled Hyperbranched Hybridization Chain Reaction

Small, EarlyView.
We report a magnetic particle anchored locked aptamer platform integrated with hyperbranched HCR and DNAzyme amplification for enzyme‐free, ultrasensitive detection of cardiac troponin I. The assay achieves a 0.25 ng/L detection limit within 25 minutes and enables cross‐species MI detection, with machine learning classification reaching 90% accuracy ...
Sayantan Tripathy, Sahil Sharma, Ng Ka Wai, Siddhant Jaitpal, Anthony Dongchau, Saugat Bhattacharyya, Sonya R. Wesselowski, Ashley B. Saunders, Gerard L. Coté, Samuel B. Mabbott   +9 more
wiley   +1 more source

Development of Advanced Nanobiosensors and a Portable Monitoring System for Pesticide Detection at the Point of Need. [PDF]

Biosensors (Basel)
Skotadis E, Tsigkourakos M, Anthoulakis E, Filippidou MK, Ntouskas S, Kainourgiaki M, Tsioustas C, Panagopoulou C, Dimou-Sakellariou S, Kalatzis N, Petrakis EA, Alexis N, Tsekenis G, Tserepi A, Chatzandroulis S, Tsoukalas D.   +15 more
europepmc   +1 more source

Selective Lipoprotein Removal Enables High‐Purity EV Isolation from Plasma via Aptamer‐Based Mesh Filtration

Small, EarlyView.
A novel affinity‐based mesh filtration system, ApoFilter, enables selective removal of plasma lipoproteins via sequential aptamer‐functionalized layers targeting ApoA1 and ApoB100. While EVs pass through unimpeded, (V)LDL and HDL are rapidly depleted.
SoYoung Jeon, YongWoo Kim, Sehyun Shin
wiley   +1 more source

Engineered anchoring aptamers induce relocalization and functional inactivation of transcription factors. [PDF]

Sci Adv
Ling N, Wu H, Zhang Y, Yao S, Liu F, Tang X, Xie T, Yuan Y, Wei X, Dai J, Chen W, Yan M, Wang Z, Peng T, Zhang Y, Wang H, Wu J, Ye M, Wu W.   +18 more
europepmc   +1 more source

Motorized DNAzymes Drive Enhanced Electrochemical Biosensing for Rapid Bacterial Detection

Small Methods, EarlyView.
The micromotor DNAzyme analyzer (Motolyzer) enables sensitive electrochemical detection of Legionella pneumophila proteins in unprocessed samples with high specificity. Upon target recognition, DNAzymes actively release redox barcodes, which are detected on DNA‐functionalized electrodes.
Amir Ali Akhlaghi, Sadman Sakib, Roderick MacLachlan, Jinal Manek, Enas Osman, Survanshu Saxena, Ehsan Heydarian Dolatabadi, Jimmy Gu, Yingfu Li, Leyla Soleymani   +9 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next-Generation Diagnostics and Biosensing. [PDF]

Adv Sci (Weinh)
Nguyen JVL, Meziadi A, Brunner C, McKeague M, Malic L, Tabrizian M.   +5 more
europepmc   +1 more source

Advances in cholesterol and lipoproteins detection for healthcare: A review

VIEW, EarlyView.
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta, Somayeh Fardindoost, Azadeh Abdi, Kaveh Yazdani, Longfei Yin, Syamak Farajikhah, Mina Hoorfar, Fariba Dehghani   +7 more
wiley   +1 more source

Aptamers as emerging tools for plant disease management: From biosensing to active modulation. [PDF]

iScience
Liu F, Zhang Y, Wei Z, Wu H, Jia Y, Li X.   +5 more
europepmc   +1 more source