Results 131 to 140 of about 83,758 (359)

The Central role of KNG1 gene as a genetic determinant of coagulation pathway-related traits: Exploring metaphenotypes [PDF]

, 2016
Traditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same biological process, we introduce ...
Brunel, Helena, Martin-Fernandez, Laura, Martinez Perez, Angel, Massanet, Raimon, Perera Lluna, Alexandre, Soria, José Manuel, Souto, Juan Carlos, Ziyatdinov, Andrey   +7 more
core   +4 more sources

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

Platelet Counts and Coagulation Tests Prior to Neuraxial Anesthesia in Patients With Preeclampsia: A Retrospective Analysis [PDF]

, 2013
This retrospective, descriptive study aimed to assess hematologic testing practices in 100 patients with preeclampsia undergoing neuraxial blockade (NB).
Butwick, A, Sultan, P
core  

Safety, Efficacy and Treatment Patterns of rIX‐FP in Previously Untreated Paediatric Haemophilia B Patients: A Retrospective Chart Review in Japan

Haemophilia, EarlyView.
Abstract Background Limited real‐world data exist on recombinant fusion protein‐linking coagulation factor IX (FIX) with albumin (rIX‐FP) in paediatric previously untreated patients (PUPs) with haemophilia B, particularly in infants. Aims To evaluate the treatment patterns, safety and efficacy of rIX‐FP in paediatric PUPs in Japan.
Keiji Nogami, Chiai Nagae, Masatoshi Yono, Naoki Terasaka   +3 more
wiley   +1 more source

Relationship between plasma dabigatran concentration and activated partial thromboplastin time in Japanese patients with non-valvular atrial fibrillation

Journal of Arrhythmia, 2015
Background: Activated partial thromboplastin time (aPTT) is recommended for monitoring anticoagulant activity in dabigatran-treated patients; however, there are limited data in Japanese patients.
Daiki Shimomura, Yoshihisa Nakagawa, MD, Hirokazu Kondo, MD, Toshihiro Tamura, MD, Masashi Amano, MD, Yukiko Hayama, MD, Naoaki Onishi, MD, Yodo Tamaki, MD, Makoto Miyake, MD, Kazuaki Kaitani, MD, Chisato Izumi, MD, Masahiko Hayashida, Aya Fukuda, Fumihiko Nakamura, MD, Seiji Kawano, MD   +14 more
doaj   +1 more source

Comparison of thromboelastometry (ROTEM®) with standard plasmatic coagulation testing in paediatric surgery [PDF]

, 2017
Background Thromboelastometry (ROTEM®) might be useful to detect intraoperative coagulation disorders early in major paediatric surgery. This observational trial compares this technique to standard coagulation tests. Methods Intraoperative blood sampling
Haas, T., Madjdpour, C., Mauch, J., Schmugge, M., Speer, O., Spielmann, N., Weiss, M.   +6 more
core   +1 more source

Post‑Marketing Surveillance of the Safety and Effectiveness of Emicizumab in Japanese Patients With Congenital Haemophilia A With Inhibitors

Haemophilia, EarlyView.
ABSTRACT Introduction The bispecific monoclonal antibody emicizumab was approved for prophylactic treatment of congenital haemophilia A (HA) in Japan in 2018. Aim To monitor long‐term safety and effectiveness of emicizumab, including appropriate concomitant use of bypassing agents (BPAs), in Japanese patients with congenital HA with inhibitors who ...
Midori Shima, Katsuyuki Fukutake, Masanori Matsumoto, Yoshihiko Sugimura, Chiaki Sugita, Lyu Ji, Mika Kawano, Tadashi Matsushita   +7 more
wiley   +1 more source

Feminization and severe pancytopenia caused by testicular neoplasia in a cryptorchid dog [PDF]

, 2016
In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens.
Hebbelinck, Lien, Kitshoff, Adriaan, Paepe, Dominique, Vandenabeele, Sophie   +3 more
core  

Monitoring Heparin Therapy: APTT Results From Partial-vsFull-Draw Tubes [PDF]

, 1998
J. Siegel, David W. Bernard, Vanlila K. Swami, Kathleen Sazama   +3 more
openalex   +1 more source

Monitoring of Nonacog Beta Pegol: One‐Stage Clotting Assay With Kaolin Reagent as a Practical Alternative to Chromogenic Methods

Haemophilia, EarlyView.
ABSTRACT Introduction Accurate monitoring of nonacog beta pegol (N9‐GP) is essential to ensure appropriate treatment and to avoid under‐ or overdosing, which may result in clinical complications. The product's extended half‐life, achieved through molecular modification, poses challenges for activity measurement, particularly when using a one‐stage ...
Marie Prudková, Petr Smejkal, Dagmar Chytrá, Jiřina Zavřelová, Gabriela Romanová, Miroslav Penka, Alena Buliková   +6 more
wiley   +1 more source