Results 151 to 160 of about 49,590 (251)

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, Volume 38, Issue 60, 27 October 2026.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Perioperative management of acute type A aortic dissection using extended half-life factor IX (Alprolix) in a patient with severe hemophilia B: a case report. [PDF]

Gen Thorac Cardiovasc Surg Cases
Kitamura T, Ryu Y, Nakaji S, Taniguchi S.   +3 more
europepmc   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, Volume 13, Issue 55, 5 October 2026.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

Normal thromboelastography with a markedly prolonged activated partial thromboplastin time in severe prekallikrein deficiency: Implications for perioperative hemostatic assessment. [PDF]

Transfusion
Abstract Background Prekallikrein (PK) deficiency is a rare contact factor deficiency that can markedly prolong the activated partial thromboplastin time (aPTT) without a bleeding phenotype. Because viscoelastic hemostatic assays also rely on contact activation, their behavior in severe PK deficiency is relevant to perioperative evaluation of isolated ...
Jacobs JW, Matafonov A, Baxter PG, Cheng Q, Booth GS, Sharma D, Tillman BF, Gailani D.   +7 more
europepmc   +2 more sources

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, Volume 16, Issue 10, Page 1094-1106, October 2026.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial. [PDF]

Nat Commun
Chaponda M, Gwasupika J, Connon R, Tshilab Kabwit P, Miti S, Obonyo N, Gibb DM, Williams TN, Day NPJ, Dondorp AM, Walker AS, George EC, Maitland K.   +12 more
europepmc   +1 more source

Traction‐Induced Avulsion of an Iliocaval Venous Branch During Multilevel OLIF for Degenerative Scoliosis: Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Adult degenerative scoliosis can be effectively treated with lateral or oblique lumbar interbody fusion (LLIF/OLIF), but vascular injury remains a rare and potentially catastrophic complication. We report the case of a 78‐year‐old woman with long‐standing degenerative scoliosis who underwent multilevel OLIF from L2 to L5.
Tetsuro Ohba, Nobuki Tanaka, Kotaro Oda, Hayato Takei, Kai Mizukami, Go Goto, Hirotaka Haro   +6 more
wiley   +1 more source

Method Comparison of PT, INR, and aPTT Results Obtained Using Two Coagulation Analyzers in Routine Laboratory Practice. [PDF]

Diagnostics (Basel)
Özbek Kurtul B, Dündar B, Gündoğan Gİ, Sevinc SK, Elgün T, Yurttaş AG.   +5 more
europepmc   +1 more source