Results 11 to 20 of about 62,888 (279)

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers [PDF]

, 2010
The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients
Braun, Jean-Pierre, Geffré, Anne, Grollier, Sophie, Hanot, Camille, Trumel, Catherine, Vergez, François   +5 more
core   +1 more source

Influence of vitamin K antagonist treatment on activated partial thromboplastin time [PDF]

, 2015
A
Devreese, Katrien, MULLIEZ, SYLVIE, Van den Bogaert, Julie   +2 more
core   +2 more sources

Diagnostic Pitfalls in a Man with Systemic Lupus Erythematous

European Journal of Case Reports in Internal Medicine, 2019
Systemic lupus erythematosus (SLE) is a chronic multi-systemic immune-mediated disease with confusing symptoms and delayed diagnosis. We report the case of a 32-year-old man with a persistent Venereal Disease Research Laboratory (VDRL)-positive reaction ...
Andrei Cristian Dan Gheorghe, Andreea Simona Hodorogea, Cristina Elena Georgescu, Ana Ciobanu, Ioan Tiberiu Nanea, Gabriela Silvia Gheorghe   +5 more
doaj   +1 more source

Evaluation of an Unfractioned Heparin Pharmacy Dosing Protocol for the Treatment of Venous Thromboembolism in Nonobese, Obese, and Severely Obese Patients [PDF]

, 2017
Background: Despite large interpatient variability in dose response, heparin is utilized for treatment of venous thromboembolism (VTE). Current data on the optimal heparin dosing in obese patients are conflicting. Objective: The objective was to evaluate
Breedlove, Emily Y., Hosch, Lindsey M., Knoderer, Chad A., Scono, Lauren E.   +3 more
core   +2 more sources

Investigation of sensitivity for coagulation factor deficiency in APTT and PT: how to perform it? [PDF]

Clinical Chemistry and Laboratory Medicine, 2016
Katrien Devreese
exaly   +3 more sources

Monitoring of Unfractionated Heparin in Severe COVID-19: An Observational Study of Patients on CRRT and ECMO

TH Open, 2020
Objective Severe cases of coronavirus disease 2019 (COVID-19) can require continuous renal replacement therapy (CRRT) and/or extracorporeal membrane oxygenation (ECMO).
Alexander S. Streng, Thijs S.R. Delnoij, Mark M.G. Mulder, Jan Willem E.M. Sels, Rick J.H. Wetzels, Paul W.M. Verhezen, Renske H. Olie, Jeroen P. Kooman, Sander M.J. van Kuijk, Lloyd Brandts, Hugo ten Cate, Roberto Lorusso, Iwan C.C. van der Horst, Bas C.T. van Bussel, Yvonne M.C. Henskens   +14 more
doaj   +1 more source

Global Thrombosis Test - a possible monitoring system for the effects and safety of dabigatran [PDF]

, 2015
© Otsui et al. 2015BACKGROUND: Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a
Gorog, Diana A, Inoue, Nobutaka, Iwata, Sachiyo, Otsui, Kazunori, Ozawa, Toru, Suzuki, Atsushi, Takei, Asumi, Yamamoto, Junichiro, Yoshioka, Takayuki   +8 more
core   +2 more sources

Abnormal coagulation profile in people living with HIV-AIDS on combined Antiretroviral Therapy: findings from a case-control study in the Ho municipality, Ghana

The Pan African Medical Journal, 2018
INTRODUCTION: Although combined Anti-Retroviral Therapy (cART) has improved the quality of life and survival in people living with HIV-AIDS (PLWHA), there have been reports of increased non-AIDS related co-morbidities such as coagulopathies.
Richard Kobina Dadzie Ephraim, James Elikem Ahadzie, Patrick Adu, Joseph Boachie, Hope Agbodzakey, Prince Adoba, Obed Cudjoe   +6 more
doaj   +1 more source

Activated partial thromboplastin time maybe associated with the prognosis of papillary thyroid carcinoma

Open Chemistry, 2022
Hemostasis markers associated with tumors have been widely studied. However, the associations between the coagulation factors and papillary thyroid carcinoma (PTC) prognosis remain unclear.
Wang Yanhai, Liu Luying, Zhou Pingting, Luo Xiaoli, Liu Han-Qing, Yang Hua   +5 more
doaj   +1 more source