Results 191 to 200 of about 59,602 (254)

How to Optimize Activated Partial Thromboplastin Time (APTT) Testing: Solutions to Establishing and Verifying Normal Reference Intervals and Assessing APTT Reagents for Sensitivity to Heparin, Lupus Anticoagulant, and Clotting Factors

Seminars in Thrombosis and Hemostasis, 2019
The activated partial thromboplastin time (APTT) assay is a very common coagulation test, used for several reasons. The test is conventionally used for assessing the contact factor (intrinsic) pathway of blood coagulation, and thus for screening ...
E. Favaloro, G. Kershaw, S. Mohammed, G. Lippi   +3 more
semanticscholar   +1 more source

Effect of an activated charcoal product (DOAC Stop™) intended for extracting DOACs on various other APTT-prolonging anticoagulants

Clinical Chemistry and Laboratory Medicine, 2019
Background The aim of the study was to investigate the specificity of an activated charcoal-based product (DOAC Stop™) initially intended for the specific extraction of direct oral anticoagulants (DOACs) from test plasmas on a range of other ...
T. Exner, M. Ahuja, Lisa Ellwood
semanticscholar   +1 more source

Monitoring heparin treatment with the APTT: the effect of methodological changes on the APTT

The Netherlands Journal of Medicine, 1996
To assess the effect on the desired activated partial thromboplastin time (APTT) of altered practice in the laboratory control of heparin treatment.Descriptive study of the number of APTTs in the desired range (DR) in 1987 (historical controls) and in 1992/1993.
J W, Krulder, F J, van der Meer, E, Briët, A E, Meinders   +3 more
openaire   +2 more sources

Spontanhämatome bei isoliert erhöhter aPTT

Praxis, 2011
Wir berichten über eine 64-jährige Patientin mit Spontanhämatomen. Eine Blutungsneigung war bisher nicht bekannt. Die Gerinnungsabklärung ergab eine isoliert verlängerte aPTT. Als Ursache konnte ein Inhibitor gegen Faktor VIII ohne fassbare Ursache (idiopathische Hemmkörperhämophilie) gefunden werden.
null Heimgartner, null Oestmann, null Keller, null Rüsges-Wolter   +3 more
openaire   +1 more source

PT AND aPTT TRENDS IN DENGUE FEVER

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, 2022
Dengue is the the most common mosquito borne arboviral disease in tropical regions of the world. Common hematological abnormalities seen with dengue fever are leukopenia followed by thrombocytopenia. Coagulopathy may also be seen in dengue fever. This study aims to observe the trends of PT and aPTT prole in dengue fever.
Ammanabrolu Sreekavya, Kamsala Chakricharan, V. Mahesh   +2 more
openaire   +1 more source

Variability in Heparin Sensitivity of APTT Reagents

American Journal of Clinical Pathology, 1986
Activated partial thromboplastin time (APTT) is the most widely used coagulation test for monitoring heparin therapy. This study quantitates the differences in heparin sensitivity of seven commercially available APTT reagents, using plasma samples obtained from 20 subjects. The reagents studied were Actin, Actin FS, Automated APTT, Cephotest, Coagachek
T D, Bjornsson, P V, Nash
openaire   +2 more sources

An Analysis of the Sensitivity of the Activated Partial Thromboplastin Time (APTT) Assay, as Used in a Large Laboratory Network, to Coagulation Factor Deficiencies.

American Journal of Clinical Pathology, 2022
Louis Do, E. Favaloro, Leonardo Pasalic
semanticscholar   +1 more source

Comparison of Two APTT Methods of Monitoring Heparin Therapy: APTT Ratio and Heparin Response of Pooled Normal Plasma

American Journal of Clinical Pathology, 1990
The sensitivity of the reagents for activated partial thromboplastin time (APTT) test varies greatly. Consequently the physicians who prescribe heparin based on certain APTT ratios may order different doses of heparin and produce different levels of anticoagulation in their patients, depending on the sensitivity of APTT reagent used by the laboratory ...
B, Zanke, A M, Shojania
openaire   +2 more sources

STANDARDIZATION OF THE APTT TEST CURRENT STATUS

Scandinavian Journal of Haematology, 1980
The partial thromboplastin time (PTT) which is used as an overall measure of the intrinsic clotting system, is the commonest coagulation test employed in routine laboratories apart from the prothrombin time. The main functions of the test are: 1. to screen intrinsic coagulation defects; 2. to control heparin administration; 3.
openaire   +2 more sources

Performance characteristics of a new synthetic APTT reagent

Clinical & Laboratory Haematology, 1998
Performance characteristics of a totally synthetic activated partial thromboplastin time (APTT) reagent, recently available commercially, were evaluated and compared with a rabbit-brain extracted reagent. We found that the synthetic reagent, Synthasil, returned significantly higher normal APTT values than the brain-extracted reagent, Thrombosil.
C, Ts'ao, D, Neofotistos, M, Oropeza, M, Rogan, M, Santos   +4 more
openaire   +2 more sources