Results 191 to 200 of about 45,024 (296)

The Structure-Activity Relationship and Anticoagulation Mechanism of Polyglycerol Sulfates of Different Architectures. [PDF]

open access: yesBiomacromolecules
Krage C   +6 more
europepmc   +1 more source

Diagnosing and Managing Paradoxical Deep Vein Thrombosis in a Patient With Congenital Afibrinogenemia

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Congenital afibrinogenemia, classically a bleeding disorder, can paradoxically predispose to thrombosis, potentially due to disruptions in fibrin‐mediated thrombin clearance and plasmin activation. A young man with reported congenital afibrinogenemia presented with extensive deep vein thrombosis in the setting of undetectable fibrinogen and ...
Altamash Jawadi   +9 more
wiley   +1 more source

Multi‐Layered Genomic and Clinical Analysis Identifies Novel Variants, Co‐Occurring Single Nucleotide Polymorphism Pairs, and Clinical Determinants of Host‐Pathogen Interaction in COVID‐19 Severity

open access: yesJournal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Host genetic factors may contribute to COVID‐19 severity. To identify genetic variants influencing COVID‐19 severity progression, whole‐exome sequencing was performed, followed by an exome‐wide association study on 191 hospitalized patients categorized into three severity groups.
Doris Repušić   +7 more
wiley   +1 more source

Multiple Reassortments, Limited Geographic Spread, and Comparable Pathogenicity of Crimean‐Congo Hemorrhagic Fever Viruses in Sivas Province, Türkiye

open access: yesJournal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Crimean‐Congo hemorrhagic fever virus (CCHFV) is a segmented RNA virus that can cause severe hemorrhagic fever and is primarily transmitted to humans and other mammals through tick bites. Since segment reassortment can increase genetic diversity and disease severity, we sampled infected ticks and humans in Sivas Province, Türkiye, a region ...
Qianying Lin   +15 more
wiley   +1 more source

Fully Synthetic, Biomimicking Polysulfates With Tunable Anticoagulant and Endothelial Cell–Selective Bioactivity

open access: yesMacromolecular Bioscience, Volume 26, Issue 6, June 2026.
Sulfated PHEMA‐based polyelectrolyte brushes are introduced as a reductionist platform to probe glycosaminoglycan‐inspired bioactivity. High charge density governs growth factor interactions and is associated with distinct vascular cell responses, enabling balanced endothelial and smooth muscle cell co‐culture.
Andrea Cosimi   +9 more
wiley   +1 more source

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