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Physiological roles of glycerol-transporting aquaporins: the aquaglyceroporins
Cellular and Molecular Life Sciences, 2006A subclass of aquaporin (AQP) water channels, termed aquaglyceroporins, are also able to transport glycerol and perhaps urea and other small solutes. Although extensive data exist on the physiological roles of aquaporin-facilitated water transport, until recently the biological significance of glycerol transport by the mammalian aquaglyceroporins has ...
M, Hara-Chikuma, A S, Verkman
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Revisiting the metabolic syndrome: the emerging role of aquaglyceroporins
Cellular and Molecular Life Sciences, 2018The metabolic syndrome (MetS) includes a group of medical conditions such as insulin resistance (IR), dyslipidemia and hypertension, all associated with an increased risk for cardiovascular disease. Increased visceral and ectopic fat deposition are also key features in the development of IR and MetS, with pathophysiological sequels on adipose tissue ...
Inês Vieira da Silva +4 more
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The involvement of aquaglyceroporins in transport of boron in barley roots
Plant, Cell & Environment, 2009ABSTRACTBoron (B) enters cells as the uncharged boric acid, a small neutral molecule with sufficient lipid solubility to cross cell membranes without the aid of transport proteins. The extent to which the observed uptake rates for B in plants can be explained by this simple physical process was examined by applying treatments expected to inhibit the ...
Fitzpatrick, K., Reid, R.
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Hypogonadism and aquaglyceroporins in Sertoli cells
2023Male hypogonadism is a hormonal pathology characterized by low plasma testosterone levels. Decreased circulating testosterone levels are known to be directly related to poor fertility outcomes and decreased sperm quality. Sertoli cells (SCs) ensure an adequate ionic and nutritional environment for spermatogenesis.
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Roles of Vertebrate Aquaglyceroporins in Arsenic Transport and Detoxification
2010Aquaporins are important channel proteins that are responsible for the balance of cellular osmolarity and nutrient transport in vertebrates. Recently, new functions of these ancient channels have been found in the conduction of metalloid arsenic (As).
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Arsenic and Vertebrate Aquaglyceroporins
2013Joseph R. McDermott, Zijuan Liu
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Featured System Aquaglyceroporin
Protein Structure Initiative Structural Genomics Knowledgebase, 2009openaire +1 more source