Results 91 to 100 of about 24,621,355 (297)
Urinary extracellular vesicular release of aquaporins in patients with renal transplantation
BMC Nephrology, 2019 Background Diuresis has been observed within a week following renal transplantation, suggesting that the procedure causes acute disturbance of renal water homeostasis. Aquaporin (AQP) 1 and AQP2, important proteins for renal water reabsorption, have been
Sayaka Oshikawa-Hori +3 more
doaj +1 more source
Diabetes Insipidus in Mice with a Mutation in Aquaporin-2
PLoS Genetics, 2005 Congenital nephrogenic diabetes insipidus (NDI) is a disease characterized by failure of the kidney to concentrate urine in response to vasopressin. Human kindreds with nephrogenic diabetes insipidus have been found to harbor mutations in the vasopressin receptor 2 (Avpr2) gene or the vasopressin-sensitive water channel aquaporin-2 (Aqp2) gene ...
David J Lloyd +3 more
openaire +4 more sources
MSMS data for two peptides of aquaporin 2.
, 2013 MSMS data for two peptides of aquaporin 2.
Kirill S. Kireev (445039) +10 more
core +1 more source
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
Advanced Science, EarlyView.A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao +10 more
wiley +1 more source
Dexamethasone enhances vasopressin-induced aquaporin-2 gene expression in the mpkCCD cells
, 2018 The mouse cortical collecting duct cell (mpkCCD) has been an instrumental cell model for studying vasopressin-mediated aquaporin-2 regulation. This cell line was first developed by Vandewalle’s group from a transgenic mouse carrying the transforming SV40
Kuang-Ting Kuo +2 more
core +1 more source
Advanced Science, EarlyView.Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han +11 more
wiley +1 more source
Increased T-cell immunity against aquaporin-4 and proteolipid protein in neuromyelitis optica. [PDF]
, 2011 In neuromyelitis optica (NMO), B-cell autoimmunity to aquaporin-4 (AQP4) has been shown to be essential. However, the role of T cells remains ambiguous. Here, we first showed an increase in CD69+ activated T cells in PBMCs during NMO relapses.
Goto, Hirofumi +19 more
core +1 more source
Annals of Neurology, EarlyView.Objective To characterize magnetic resonance imaging (MRI)‐based glymphatic surrogates in Huntington's disease (HD) using MRI measures of perivascular diffusivity and structural perivascular alterations across multiple large cohorts. Methods We analyzed 2,731 MRI sessions from 880 participants across 3 large retrospective HD cohorts.
Alexia Solomon +5 more
wiley +1 more source
Controlled aquaporin-2 expression in the hypertonic environment [PDF]
American Journal of Physiology-Cell Physiology, 2009 The corticomedullary osmolality gradient is the driving force for water reabsorption occurring in the kidney. In the collecting duct, this gradient allows luminal water to move across aquaporin (AQP) water channels, thereby increasing urine concentration. However, this same gradient exposes renal cells to great osmotic challenges.
openaire +3 more sources
The aquaporin family of water channels in kidney: An update on physiology and pathophysiology of aquaporin-2 [PDF]
, 1996 The aquaporin family of water channels in kidney: An update on physiology and pathophysiology of aquaporin-2. The long-standing problem of membrane water transport has been advanced by the recognition of a new family of water transport proteins, the ...
Frøklær, Jørgen +4 more
core +1 more source