Results 101 to 110 of about 38,256 (256)
Nature Communications, 2018 Patients suffering from congenital nephrogenic diabetes insipidus (NDI) fail to concentrate urine due to mutations in vasopressin type 2 receptor (V2R). Here Ando et al.
Fumiaki Ando +10 more
doaj +1 more source
Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran +3 more
wiley +1 more source
npj Clean WaterAquaporin (AQP) biomimetic membranes are a coming-of-age technology for water purification. Although several studies have reported aquaporin biomimetic membrane fabrication to date, these membranes show low water flux mainly due to the low porosity and ...
Ahmed Fuwad +8 more
doaj +1 more source
Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice
PROTEOMICS, EarlyView.ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min +8 more
wiley +1 more source
P46 | ANALYSIS OF AQUAPORIN-2 MUTANT MICE
European Journal of HistochemistryAquaporin-2 (AQP2), a membrane water channel protein in kidney collecting duct cells, is necessary for urine concentration regulated by vasopressin (VP).
doaj +1 more source
Intracellular Plasmodium aquaporin 2 is important for sporozoite production in the mosquito vector and malaria transmission. [PDF]
Proc Natl Acad Sci U S A, 2023 Bailey AJ +5 more
europepmc +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Portal Hypertension &Cirrhosis, EarlyView.Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus. [PDF]
Sci Rep, 2023 Hagströmer CJ +6 more
europepmc +1 more source
Sensory Neuroscience, EarlyView.Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa +5 more
wiley +1 more source
Small Methods, EarlyView.Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz +5 more
wiley +1 more source