Results 101 to 110 of about 41,663 (295)

Controlled aquaporin-2 expression in the hypertonic environment [PDF]

American Journal of Physiology-Cell Physiology, 2009
The corticomedullary osmolality gradient is the driving force for water reabsorption occurring in the kidney. In the collecting duct, this gradient allows luminal water to move across aquaporin (AQP) water channels, thereby increasing urine concentration. However, this same gradient exposes renal cells to great osmotic challenges.
openaire   +4 more sources

Hyperreflective Foci in the Inner Nuclear Layer: Proof‐of‐Concept for an Optical Coherence Tomography Derived Microglia‐Related Marker in Multiple Sclerosis

Annals of Neurology, EarlyView.
The role of microglia has emerged as a critical driver of disease progression in multiple sclerosis (MS), but we lack broadly applicable monitoring tools. Here, we investigated whether hyperreflective foci (HRF), as detected by optical coherence tomography (OCT) within the inner nuclear layer (INL) of the retina, can be used as a marker for microglial ...
Jonathan A. Gernert, Laura M. Bartos, Tara Christmann, Hanna Zausinger, Luca N. Diedrich, Daniel Engels, Miriam Schlüter, Sarah Schlaeger, Sophia Stoecklein, Leonie F. Keidel, Tania Kümpfel, Martin Kerschensteiner, Matthias Brendel, Joachim Havla   +13 more
wiley   +1 more source

Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking

Journal of Pharmacological Sciences, 2004
Targeted positioning of water channel aquaporin-2 (AQP2) strictly regulates body water homeostasis. Trafficking of AQP2 to the apical membrane is critical for the reabsorption of water in renal collecting ducts.
Yumi Noda, Sei Sasaki
doaj   +1 more source

In silico analysis of molecular mimicry between human aquaporin 3, Aspergillus fumigatus aquaporin and aquaporins from allergic sources [version 2; peer review: 2 approved]

F1000Research
Background Atopic dermatitis (AD) is a chronic inflammatory skin condition that has a significant impact on quality of life. The immune response and allergy symptoms in AD are triggered by the recognition of specific allergens by IgE antibodies.
Andrés Sánchez, Juan Urrego, Claudia Baena, Carlos Bernal, Adriana Lorduy, Jorge Sanchez, Marlon Munera, Yaquelin Padilla   +7 more
doaj   +1 more source

Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases [PDF]

, 2008
We define phosphovariants as genetic variations that change phosphorylation sites or their interacting kinases. Considering the essential role of phosphorylation in protein functions, it is highly likely that phosphovariants change protein functions and ...
Gil-Mi Ryu, Jong Hun Kim, Kyu-Won Kim, Kyung-Soo Oh, Pamela Song   +4 more
core   +1 more source

Increased CSF aquaporin-4, and interleukin-6 levels in dogs with idiopathic communicating internal hydrocephalus and a decrease after ventriculo-peritoneal shunting [PDF]

, 2016
Background: Studies in animal models, in which internal hydrocephalus has been induced by obstructing the cerebrospinal fluid pathways, have documented an up-regulation of the concentrations of aquaporin-4 (AQP4) in the brain.
Christoph Rummel, Jessica Hauer, Joachim Roth, Malgorzata Kolecka, Martin J. Schmidt, Nele Ondreka, Vanessa McClure   +6 more
core   +2 more sources

Visual Analytics for Robust Investigations of Placental Aquaporin Gene Expression in Response to Maternal SARS-CoV-2 Infection

Analytics
The human placenta is a multifunctional, disc-shaped temporary fetal organ that develops in the uterus during pregnancy, connecting the mother and the fetus.
Raphael D. Isokpehi, Amos O. Abioye, Rickeisha S. Hamilton, Jasmin C. Fryer, Antoinesha L. Hollman, Antoinette M. Destefano, Kehinde B. Ezekiel, Tyrese L. Taylor, Shawna F. Brooks, Matilda O. Johnson, Olubukola Smile, Shirma Ramroop-Butts, Angela U. Makolo, Albert G. Hayward   +13 more
doaj   +1 more source

AQP2 is Necessary for Vasopressin- and Forskolin-Mediated Filamentous Actin Depolymerization in Renal Epithelial Cells [PDF]

, 2011
Remodeling of the actin cytoskeleton is required for vasopressin (VP)‐induced aquaporin 2 (AQP2) trafficking. Here, we asked whether VP and forskolin (FK)‐mediated F‐actin depolymerization depends on AQP2 expression.
Bouley, Richard, Brown, Dennis, Lu, Hua A Jenny, Yui, Naofumi   +3 more
core   +2 more sources

Real‐time monitoring of root dielectric properties for assessing crop plant damage caused by foliar application of glyphosate

Applications in Plant Sciences, EarlyView.
Abstract Premise There is a knowledge gap regarding how foliar injury and restricted water uptake can be detected by measuring root dielectric response. This pot study nondestructively evaluated the efficiency of real‐time dielectric measurement to monitor the effects of glyphosate spraying.
Imre Cseresnyés, Anna Füzy, Tünde Takács   +2 more
wiley   +1 more source

The Aquaporin Channel Repertoire of the Tardigrade

Bioinformatics and Biology Insights, 2013
Limno-terrestrial tardigrades are small invertebrates that are subjected to periodic drought of their micro-environment. They have evolved to cope with these unfavorable conditions by anhydrobiosis, an ametabolic state of low cellular water.
Markus A. Grohme, Brahim Mali, Weronika Wełnicz, Stephanie Michel, Ralph O. Schill, Marcus Frohme   +5 more
doaj   +1 more source