Results 221 to 230 of about 75,608 (261)

Transforming Growth Factor‐β‐Mediated Fibrotic Remodeling Drives Chronic Kidney Disease in Methylmalonic Aciduria and Propionic Aciduria—Identification of a New Therapeutic Target

Journal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Propionic aciduria (PA‐uria) and methylmalonic aciduria (MMA‐uria) are caused by defects in propionate catabolism. While chronic kidney disease (CKD) is a well‐established complication in MMA‐uria, renal involvement in PA‐uria has only come into focus more recently, and the underlying mechanisms remain poorly understood.
Karina A. Zeyer, Stefan Tholen, Oliver Schilling, Leonie Gerling, Marina Morath, Stefan Kölker, Alexander Nyström, Ute Spiekerkoetter, Anke Schumann   +8 more
wiley   +1 more source

Corrigendum to “Corallodiscus flabellata B.L. Burtt Extracts Stimulate Diuretic Activity and Regulate the Renal Expression of Aquaporins” [PDF]

openalex   +1 more source

What Is Your Diagnosis? Fine‐Needle Aspirate From a Lingual Mass in a Cat

Veterinary Clinical Pathology, EarlyView.
Emma Stacey, Andrii Trokoz, Kimberly Williams, Dorothee Bienzle   +3 more
wiley   +1 more source

Help from the past to cope with the future: Vitis sylvestris as a resource for abiotic stress resilience

PLANTS, PEOPLE, PLANET, Volume 7, Issue 6, Page 1629-1638, November 2025.
Viticulture is facing increasing challenges due to climate change. The focus on fast growth and sweet berries has come at the expense of stress resilience. Grafting onto Phylloxera‐resistant rootstocks from American species has been the most successful form of ecological pest management.
Samia Daldoul, Islam M. Khattab, Faouzia Hanzouli, Imane Bahlouli, Peter Nick, Ahmed Mliki, Mahmoud Gargouri   +6 more
wiley   +1 more source

Expression of Aquaporin 1 and Aquaporin 4 in the Temporal Neocortex of Patients with Parkinson's Disease

Brain Pathology, 2017
A. Hoshi, A. Tsunoda, M. Tada, M. Nishizawa, Y. Ugawa, A. Kakita   +5 more
semanticscholar   +1 more source

Size, more than oxygen need, determines the number of capillaries around a muscle fibre

Experimental Physiology, EarlyView.
Christopher S. Fry, Carlo Reggiani
wiley   +1 more source

Mechanisms of Pilocarpine‐Induced Nitric Oxide and Prostaglandin Production in Porcine Ciliary Muscle

FASEB BioAdvances, Volume 7, Issue 11, November 2025.
Pilocarpine activates M1 and M3 muscarinic receptors in porcine ciliary muscle, engaging calcium‐dependent phospholipase C (PLC), nitric oxide synthase (NOS), and cyclooxygenase (COX) pathways that increase prostaglandin E2 (PGE2) synthesis. Beyond nitric oxide (NO) modulation, PGE2 emerges as a key mediator linking muscarinic signaling to ciliary ...
Giovanna Benozzi, Emmanuel Quinteros Villarruel, Andrés F. Zuluaga, Betina Orman   +3 more
wiley   +1 more source

Protective Effect of Pediococcus pentosaceus Li05 on Constipation via TGR5/TPH1/5‐HT Activation

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The mechanism of Li05 in alleviating constipation. Li05 intervention regulated gut microbiota and bile acid metabolism, increasing 5‐HT levels through the TGR5/TPH1 activation to ameliorate constipation. ABSTRACT Pediococcus pentosaceus Li05, a strain of lactic acid bacteria isolated from the faeces of healthy volunteers, exhibited potential protective
Hui Chen, Fengjiao Wang, Shengjie Li, Longxian Lv, Hao Xu, Jiafeng Xia, Lvwan Xu, Ding Shi, Lanjuan Li   +8 more
wiley   +1 more source

Vasopressin-Independent Regulation of Aquaporin-2 by Tamoxifen in Kidney Collecting Ducts [PDF]

, 2019
Stine Julie Tingskov, Hyo‐Jung Choi, Mikkel R. Holst, Shan Hu, Chunling Li, Weidong Wang, Jørgen Frøkiær, Lene N. Nejsum, Tae‐Hwan Kwon, Rikke Nørregaard   +9 more
openalex   +1 more source

Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

Brain Pathology, Volume 35, Issue 6, November 2025.
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li, Haiping Zhou, Jiaxin Xie, Mingjia Yu, Guanyu Ye, Yuzhen Zhang, Zhentong Li, Kunxue Zhang, Jingwen Wu, Sheng Xiao, Shuxin Zeng, Yuan Chang, Kaibin Huang, Suyue Pan   +13 more
wiley   +1 more source