Results 51 to 60 of about 112,352 (360)

Regulation of Aquaporin Z osmotic permeability in ABA tri-block copolymer

AIMS Biophysics, 2015
Aquaporins are transmembrane water channel proteins present in biological plasma membranes that aid in biological water filtration processes by transporting water molecules through at high speeds, while selectively blocking out other kinds of solutes ...
Wenyuan Xie, Jason Wei Jun Low, Arunmozhiarasi Armugam, Kandiah Jeyaseelan, Yen Wah Tong   +4 more
doaj   +1 more source

Peroxiporins Are Induced upon Oxidative Stress Insult and Are Associated with Oxidative Stress Resistance in Colon Cancer Cell Lines

Antioxidants, 2021
Oxidative stress can induce genetic instability and change cellular processes, resulting in colorectal cancer. Additionally, adaptation of oxidative defense causes therapy resistance, a major obstacle in successful cancer treatment.
Ana Čipak Gašparović, Lidija Milković, Claudia Rodrigues, Monika Mlinarić, Graça Soveral   +4 more
doaj   +1 more source

Aquaporin-4 expression in distal myopathy with rimmed vacuoles

BMC Neurology, 2012
Background Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle fibers with rimmed vacuoles.
Hoshi Akihiko, Yamamoto Teiji, Kikuchi Saeko, Soeda Tomoko, Shimizu Keiko, Ugawa Yoshikazu   +5 more
doaj   +1 more source

Review: ‘Gimme five’: future challenges in multiple sclerosis. ECTRIMS Lecture 2009 [PDF]

, 2010
This article is based on the ECTRIMS lecture given at the 25th ECTRIMS meeting which was held in Düsseldorf, Germany, from 9 to 12 September 2009. Five challenges have been identified: (1) safeguarding the principles of medical ethics; (2) optimizing the
Bartholomaus I., Ben-Nun A., Bennett JL, Bielekova B., Bradl M., Chabas D., De Jager PL, De Jager PL, Dornmair K., Ferguson B., Flügel A., Frischer JM, Gold R., Gregersen JW, Han MH, Hohlfeld R., Hohlfeld R., Junker A., Kerschensteiner M., Kerschensteiner M., Kinoshita M., Korn T., Krishnamoorthy G., Kuhlmann T., Kümpfel T., Kümpfel T., Kümpfel T., Lennon VA, Linington C., Lock C., Mathey EK, Misgeld T., Platten M., Pollinger B., Polman CH, Reinhard Hohlfeld, Schluesener HJ, Seitz S., Sobottka B., Stadelmann C., Trapp BD, Trapp BD, Wiendl H., Wiendl H., Zipp F.   +44 more
core   +1 more source

Inhibitors of Mammalian Aquaporin Water Channels

International Journal of Molecular Sciences, 2019
Aquaporins (AQPs) are water channel proteins that are essential to life, being expressed in all kingdoms. In humans, there are 13 AQPs, at least one of which is found in every organ system. The structural biology of the AQP family is well-established and
Mohammed Abir-Awan, P. Kitchen, M. Salman, M. Conner, A. Conner, R. Bill   +5 more
semanticscholar   +1 more source

Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Patients carrying the carbonic anhydrase12 E143K mutation showed the dry mouth phenotype. The mechanism underlying the modulation of aquaporin 5 and function in the salivary glands by carbonic anhydrase12 remains unknown. In this study, we identified the
Soyoung Hwang, Jung Yun Kang, Min Jae Kim, Dong Min Shin, Jeong Hee Hong   +4 more
doaj   +1 more source

Hypoxia-Induced Aquaporins and Regulation of Redox Homeostasis by a Trans-Plasma Membrane Electron Transport System in Maize Roots

Antioxidants, 2022
In plants, flooding-induced oxygen deficiency causes severe stress, leading to growth reduction and yield loss. It is therefore important to understand the molecular mechanisms for adaptation to hypoxia.
Anne Hofmann, Stefanie Wienkoop, Sabine Lüthje   +2 more
doaj   +1 more source

Aquaporin-4 Functionality and Virchow-Robin Space Water Dynamics: Physiological Model for Neurovascular Coupling and Glymphatic Flow. [PDF]

, 2017
The unique properties of brain capillary endothelium, critical in maintaining the blood-brain barrier (BBB) and restricting water permeability across the BBB, have important consequences on fluid hydrodynamics inside the BBB hereto inadequately ...
Igarashi, Hironaka, Kwee, Ingrid L, Nakada, Tsutomu, Suzuki, Yuji   +3 more
core   +1 more source

Comparison of Clinical Outcomes of Transverse Myelitis Among Adults With Myelin Oligodendrocyte Glycoprotein Antibody vs Aquaporin-4 Antibody Disease

JAMA Network Open, 2019
This cross-sectional study examines clinical and radiological outcomes among patients with myelin oligodendrocyte glycoprotein (MOG) antibody (Ab) disease or aquaporin-4 (AQP4)-Ab disease after experiencing a first transverse myelitis episode.
R. Mariano, S. Messina, Kurun Kumar, W. Kuker, M. Leite, Jacqueline A Palace   +5 more
semanticscholar   +1 more source

Ammonia toxicity: from head to toe? [PDF]

, 2016
Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan, Mookerjee, Rajeshwar P., Ott, Peter, Rackayova, Veronika, Rangroo Thrane, Vinita, Rose, Christopher, Vairappan, Balasubramaniyan   +6 more
core   +1 more source