Results 21 to 30 of about 37,019 (222)

AQP1-Driven Migration Is Independent of Other Known Adverse Factors but Requires a Hypoxic Undifferentiated Cell Profile in Neuroblastoma

open access: yesChildren, 2021
Neuroblastoma is a biologically very heterogeneous tumor with its clinical manifestation ranging from spontaneous regression to highly aggressive metastatic disease.
Nicola Pini   +4 more
doaj   +1 more source

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression

open access: yesScientific Reports, 2021
Exposure to arsenic, a ubiquitous metalloid on Earth, results in human cancers. Skin cancer is the most common arsenical cancers. Both autophagy and aquaporin pathway are known to promote carcinogenesis. However, the mechanisms by which arsenic regulates
Sebastian Yu   +5 more
doaj   +1 more source

Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus

open access: yesCerebrospinal Fluid Research, 2010
The discovery of a family of membrane water channel proteins called aquaporins, and the finding that aquaporin 1 was located in the choroid plexus, has prompted interest in the role of aquaporins in cerebrospinal fluid (CSF) production and consequently ...
Pitham Tom, Owler Brian K, Wang Dongwei
doaj   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Aquaporin 1, Aquaporin 3 and Aquaporin 5 expression and EGFR mutation in malignant pleural mesotheliomas: an imunohistochemical and molecular study

open access: yesBiotechnology & Biotechnological Equipment, 2017
Malignant pleural mesothelioma is a rare and fatal malignancy. This disease is, unfortunately, at its advanced stage when it is diagnosed. Survival time is usually not more than a few months.
Ulaş Alabalık   +5 more
doaj   +1 more source

Aquaporin-10 represents an alternative pathway for glycerol efflux from human adipocytes. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Glycerol outflow from adipocytes has been considered for a decade to be mediated by aquaporin-7, an aquaglyceroporin highly expressed in the adipose tissue. Its involvement in glycerol metabolism has been widely studied also in humans. Recent
Umberto Laforenza   +2 more
doaj   +1 more source

Interferon-γ suppresses intestinal epithelial aquaporin-1 expression via Janus kinase and STAT3 activation. [PDF]

open access: yesPLoS ONE, 2015
Inflammatory bowel diseases are associated with dysregulated electrolyte and water transport and resultant diarrhea. Aquaporins are transmembrane proteins that function as water channels in intestinal epithelial cells.
Michael S Dicay   +6 more
doaj   +1 more source

Aquaporin 1 (AQP1) Expression in Healthy Dog Tears

open access: yesAnimals, 2020
Aquaporins (AQPs) are a family of thirteen membrane proteins that play an essential role in the transport of fluids across the cell plasma membrane. Recently, the expression of AQPs in different ocular tissues and their involvement in the pathophysiology
Barbara Lamagna   +5 more
doaj   +1 more source

Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Structure and Function of Aquaporins

open access: yesJournal of Pharmacological Sciences, 2004
The discovery of the water channel aquaporin has greatly expanded our understanding of the regulation of the water permeability of biological membranes.
Masato Yasui
doaj   +1 more source

Overexpression of Aquaporin 1 in Synovium Aggravates Rat Collagen-Induced Arthritis Through Regulating β-Catenin Signaling: An in vivo and in vitro Study

open access: yesJournal of Inflammation Research, 2020
Yu-rong Mu1,2 ,* Meng-yuan Zhou1,2 ,* Li Cai,3 Ming-ming Liu,1,2 Rong Li1,2 1School of Pharmacy, Anhui Medical University, Hefei, Anhui Province, People’s Republic of China; 2Inflammation and Immune Mediated Diseases Laboratory of Anhui Province ...
Mu Y, Zhou M, Cai L, Liu M, Li R
doaj  

Home - About - Disclaimer - Privacy