Fragment Screening of Human Aquaporin 1 [PDF]
International Journal of Molecular Sciences, 2016 Aquaporins (AQPs) are membrane proteins that enable water transport across cellular plasma membranes in response to osmotic gradients. Phenotypic analyses have revealed important physiological roles for AQPs, and the potential for AQP water channel modulators in various disease states has been proposed.
Janet To, Jaume Torres
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Water Channels Aquaporin 4 and -1 Expression in Subependymoma Depends on the Localization of the Tumors. [PDF]
PLoS ONE, 2015 We analyzed aquaporin 4 and -1 expression in subependymomas, benign and slow growing brain tumors WHO grade I. Ten subependymoma cases were investigated, five of the fossa inferior and five of the fossa superior.Using immunohistochemistry, we observed ...
Susan Noell +5 more
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Olfactory ensheathing glia express aquaporin 1 [PDF]
Journal of Comparative Neurology, 2010 AbstractOlfactory ensheathing glia (OEG) are distinct from other glia in their developmental origin, presence in both the peripheral and central nervous systems, and highly restricted location. OEG are present only in the olfactory lamina propria, olfactory nerve, and the outer two layers of the olfactory bulb, where they envelop bundles of olfactory ...
Shannon D, Shields +3 more
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A refined structure of human aquaporin‐1 [PDF]
FEBS Letters, 2001 A refined structure of the human water channel aquaporin‐1 is presented. The model rests on the high resolution X‐ray structure of the homologous bacterial glycerol transporter GlpF, electron crystallographic data at 3.8 Å resolution and a multiple sequence alignment of the aquaporin superfamily. The crystallographic R and free R values (36.7% and 37.8%
de Groot, B. L. +2 more
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Expression and prognostic value of aquaporin 1, 3 in cervical carcinoma in women of Uygur ethnicity from Xinjiang, China. [PDF]
PLoS ONE, 2014 BACKGROUND: Overexpression of several aquaporins has been reported in different types of human cancer but the role of aquaporins in carcinogenesis has not yet been clearly defined.
Rui Chen +4 more
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Leptin Promotes Vasculogenic Mimicry in Breast Cancer Cells by Regulating Aquaporin-1. [PDF]
Int J Mol SciHan DS, Lee EO.
europepmc +3 more sources
Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Stroke among Patients with Hypertension [PDF]
, 2020 Background: Dysregulations ofAQP7andAQP9were found to be related to lipid metabolism abnormality, which had been provento be one of the mechanisms of stroke. However, limited epidemiological studies explore the associations betweenAQP7andAQP9and the risk
Cui, Lan +6 more
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Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice [PDF]
Journal of Clinical Investigation, 1999 The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia and aquaporin-4 (AQP4) in airway epithelia. To test whether these water channels facilitate fluid movement between airspace, interstitial, and capillary compartments, we measured passive and active fluid transport in AQP1 and AQP4 knockout mice. Airspace-capillary
C, Bai +5 more
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Challenges in Commercializing Biomimetic Membranes
Membranes, 2015 The discovery of selective water channel proteins—aquaporins—has prompted growing interest in using these proteins, as the building blocks for designing new types of membranes.
Mark Perry +5 more
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Expression and Localization of aquaporin‐1 in Temporomandibular Joint Disc with Internal Derangement [PDF]
, 2012 Background: Internal derangement is the most frequent arthropathy affecting the temporomandibular joint, where its commonest form is anterior disc displacement with or without reduction.
Almeida, Luis Eduardo +7 more
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