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Aquaporin‐1 in breast cancer

APMIS, 2021
The canonical function of aquaporin (AQP) water channels is to facilitate passive transport of water across cellular membranes making them essential in the regulation of body water homeostasis. Moreover, AQPs, including AQP1, have been found to be overexpressed in multiple cancer types, including breast cancer, where AQP1 overexpression is associated ...
Traberg-Nyborg, Laura   +5 more
openaire   +3 more sources

Increased Expression of Aquaporin-1 and Aquaporin-3 in Pterygium

Cornea, 2013
Recent studies have shown that aquaporins (AQPs) play an important role in proliferating tumor microvessels and angiogenesis. In this study, the authors investigated the expression of aquaporin-1 (AQP1) and aquaporin-3 (AQP3) in pterygial and normal conjunctival tissues.Fifteen patients with pterygium were enrolled in the study.
Demir, Selim   +3 more
openaire   +3 more sources

Structure and dynamics of aquaporin-1

2020
Structural response of a AQP1 is examined by a coarse-grained model with a phenomenological interaction potential with a knowledge-based residue-residue interaction (derived from an ensemble of protein structures in PDB). The thermal response of the protein chain exhibits an unexpected characteristics in its native phase where the radius of gyration of
Rangubpit, Warin   +2 more
openaire   +2 more sources

Hydrocephalus and Aquaporins: The Role of Aquaporin-1

2011
Aquaporins (AQPs) are membrane proteins that facilitate water and small solute movement in tissues. Hydrocephalus is a major central nervous system disorder associated with defective cerebrospinal fluid (CSF) turnover. Aquaporin-1 (AQP1) is a water channel located mainly at the choroid plexus epithelium and plays an active role in CSF production.
M Y S, Kalani   +2 more
openaire   +2 more sources

Aquaporin 1 expression in cystic hemangioblastomas

Neuroscience Letters, 2006
Hemangioblastomas of the central nervous system (CNS) become clinically manifest through the development of huge associated cysts. The mechanism underlying these fluid collections is as yet largely unexplained. Aquaporins (AQPs) are cell proteins responsible for transmembrane water transport that have been extensively studied in the last 10 years.
Longatti P   +4 more
openaire   +3 more sources

Clinical application of aquaporin research: aquaporin-1 in the peritoneal membrane

Pflügers Archiv - European Journal of Physiology, 2007
Peritoneal dialysis (PD) is an established mode of renal replacement therapy based on the exchange of fluid and solutes between blood and a dialysate that has been instilled in the peritoneal cavity. The dialysis process involves osmosis, as well as diffusive and convective transports through the highly vascularized peritoneal membrane.
Tomoya, Nishino, Olivier, Devuyst
openaire   +2 more sources

Expression of Aquaporin-1, Aquaporin-3, and Aquaporin-5 Correlates with Nodal Metastasis in Colon Cancer

Oncology, 2015
<b><i>Objectives:</i></b> The clinical significance of aquaporin-1 (AQP1), aquaporin-3 (AQP3), and aquaporin-5 (AQP5) expression was analyzed in a large number of patients with colon cancer. <b><i>Methods:</i></b> AQP1, AQP3, and AQP5 expression was investigated based on the immunohistochemistry of tissue
Byung Woog Kang   +10 more
openaire   +2 more sources

Renal expression and functions of aquaporin 1 and aquaporin 4 in cattle

Biotechnic & Histochemistry, 2013
Aquaporin (AQP) 1 and AQP 4 are members of the aquaporin water channel family that play an important role in reabsorption of water from the renal tubular fluid to concentrate urine. Studies of renal AQPs have been performed in human, rodents, sheep, dogs and horses.
K, Altunbas   +3 more
openaire   +2 more sources

Aquaporin-1 Antibody in Neuromyelitis Optica Patients

European Neurology, 2014
<b><i>Background/Methods:</i></b> To find out the prevalence of aquaporin-antibody (Aqp-Ab) and characterize Aqp-Ab associated clinical features in NMO, Aqp-1 and Aqp-4-Abs were examined using radioimmunoprecipitation and cell-based assays, respectively.
Erdem, Tüzün   +10 more
openaire   +2 more sources

Aquaporin 1 expression in human temporomandibular disc

Acta Histochemica, 2012
Aquaporins (AQPs) are a family of hydrophobic membrane channel proteins. The expression of several AQP isoforms has been investigated in different human tissues, including the orofacial region. However, information on the role and localization of AQP1 in joints is limited, and no data are available on aquaporins in the normal temporomandibular joint ...
LORETO, CARLA AGATA   +8 more
openaire   +3 more sources

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