Results 111 to 120 of about 36,778 (260)

Differential effects of taurine treatment and taurine deficiency on the outcome of renal ischemia reperfusion injury

Journal of Biomedical Science, 2010
Taurine possesses membrane stabilization, osmoregulatory and antioxidant properties, aspects of relevance to ischemic injury. We tested the hypothesis that body taurine status is a determinant of renal ischemic injury.
Mozaffari Mahmood S, Abdelsayed Rafik, Patel Champa, Wimborne Hereward, Liu Jun, Schaffer Stephen W   +5 more
doaj   +1 more source

Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63.

The Journal of biological chemistry, 2002
Aquaporins (AQP) were originally regarded as plasma membrane channels that are freely permeated by water or small uncharged solutes but not by ions. Unlike other aquaporins, AQP6 overexpressed in Xenopus laevis oocytes was previously found to exhibit Hg2+ or pH-activated ion conductance.
Yasui, Masato, Agre, Peter, Guggino, William B., Kozono, David, Beitz, Eric, Ikeda, Masahiro   +5 more
openaire   +2 more sources

Longitudinal changes in peritoneal solute transport rate and the impact of lower glucose degradation product glucose dialysates

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 471-478, June 2025.
Abstract Introduction Peritoneal solute transfer rates (PSTR) are reported to increase with time. Changes in PSTR were reviewed in long‐term peritoneal dialysis (PD) patients to determine whether lower glucose degradation products (low GDP) dialysates prevented an increase in PSTR. Methods PSTR was determined with a 4‐h peritoneal equilibrium test with
Andrew Davenport
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Clinicopathological Features of Pakistani Patients with Anti Aquaporin-4 (Aqp-4) Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD): A Comparison with Local, Regional and International StudiesOPTICA SPECTRUM DISORDER(NMOSD)-A COMPARISON WITH LOCAL, REGIONAL AND INTERNATIONAL STUDIES

Pakistan Armed Forces Medical Journal
  Objective: To characterize clinicopathological characteristics of patients with anti AQP-4 antibody positive Neuromyelitis Optica Spectrum Disorder in local population in order to facilitate clinicians in timely diagnosis and treatment of this rare ...
Muhammad Zain Arshad, Muhammad Omair Riaz, Dawood Ahmad, Muhammad Hussain, Ayesha Tanveer, Muhammad Aftab Hassan   +5 more
doaj   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

Brain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle, Isabella Boesgaard, Austyn Roseborough, Meaghan Frank, Qi Zhang, Stephen H. Pasternak, Robert Hammond, Shawn N. Whitehead   +7 more
wiley   +1 more source

The Aquaporin Gene SbPIP1;2 Is Involved in Dormancy Release and Regulated Under Low Temperatures in Lilium ‘Siberia’

Horticulturae
The dormancy of lilies is an important physiological process involving vernalisation and the differentiation and maturation of flower buds. We have cloned an aquaporin, SbP1P1;2, from the Lilium ‘Siberia’. Subcellular localisation analysis indicates that
Xuanmei Cai, Mingli Ke, Danfeng Ge, Zhimin Lin   +3 more
doaj   +1 more source

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

Brain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova, Ondrej Bernatik, Katarina Cimborova, Martin Barak, Michal Hendrych, Karolina Kocourkova, Marie Sulcova, Jaroslav Olha, Katerina Amruz Cerna, Zdenek Hodny, Radim Jancalek, Dasa Bohaciakova   +11 more
wiley   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

Neuromyelitis optica spectrum disorders with aquaporin-4 antibodies in patients with systemic rheumatic diseases

Неврология, нейропсихиатрия, психосоматика
Neuromyelitis optica spectrum disorder (NMOSD) with antibodies to aquaporin-4 (AQP4-IgG) is a severe autoimmune disorder of the central nervous system.
A. D. Kukushkina, V. S. Rogovskii, M. V. Melnikov, A. N. Boyko   +3 more
doaj   +1 more source