Abstract Ageing is associated with loss of skeletal muscle mass and strength (sarcopenia) and disrupted redox homeostasis. Redox signalling is essential for muscle adaptation, yet the mechanisms by which ageing disrupts cysteine‐based regulation are poorly defined. The drivers of site‐specific reactivity and signalling specificity in aged muscle remain
Ufuk Ersoy, Malcolm J. Jackson
wiley +1 more source
TMEM16A channel signalling microdomains in the regulation of vascular function
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
Genome-wide analysis of expansin and aquaporin genes and their association with auxin-related metabolites during flower opening in <i>Lonicera macranthoides</i>. [PDF]
Chen Z +8 more
europepmc +1 more source
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass +2 more
wiley +1 more source
Transcriptional changes of aquaporin genes in leaves of black medic induced by arbuscular mycorrhizal fungal inoculation under water deficit. [PDF]
Yurkov AP +3 more
europepmc +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
Müller Glia–Vasculature Interactions in the Developing Retina
Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi +6 more
wiley +1 more source
Erratum: [Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis. [PDF]
Xu J, Yang L, Dong L.
europepmc +1 more source
Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States
Proximity labeling enables cell‐type‐specific and spatially resolved mapping of glial protein networks. Proximity labeling approaches provide insights into glial function under physiological and pathological conditions. ABSTRACT Glial cells, including radial glia, oligodendrocyte precursor cells (OPCs), oligodendrocytes, astrocytes, and microglia, are ...
João Baltar +3 more
wiley +1 more source
Influence of an AQP4 haplotype and sleep duration on early Alzheimer's disease. [PDF]
Palatsides EL +16 more
europepmc +1 more source

