Results 151 to 160 of about 36,778 (260)

Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang, Shuwen Xue, Zhi Gao, Panlai Shi, Li Wang, Qi Feng, Xiangdong Kong, Xiaofan Zhu   +7 more
wiley   +1 more source

Optimizing Rituximab Maintenance Therapy: Outcomes of Extended-Interval Dosing in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder. [PDF]

J Clin Med Res
Kittipadakul S, Ongphichetmetha T, Siritho S, Uawithya E, Prayoonwiwat N, Rattanathamsakul N, Jitprapaikulsan J.   +6 more
europepmc   +1 more source

Cinnamaldehyde From Cinnamon as a Food‐Derived Bioactive: Phytochemistry, Anticancer Mechanisms, Bioavailability, Nanoformulation and Safety

Food Frontiers, Volume 7, Issue 5, September 2026.
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi, Sally Kamau, Gulnaz Seitimova, Shynar Zhumagaliyeva, Javad Sharifi‐Rad, William N. Setzer, Daniela Calina   +6 more
wiley   +1 more source

Intracranial inflammation and meningeal fibrosis are associated with perivascular changes, altered CSF tracer dynamics, and cognitive decline in a rat model of communicating hydrocephalus. [PDF]

Fluids Barriers CNS
Wang CL, Tseng GF, Tsai ST, Chen LJ.
europepmc   +1 more source

A TREK‐1/AQP4/TRPA1/BDNF Signaling Axis Is Associated With Astrocytic Volume Transients, Synaptic Plasticity, and Spatial Memory

Glia, Volume 74, Issue 9, September 2026.
Astrocytic TREK‐1‐dependent volume transients contribute to hippocampal synaptic plasticity and memory formation. TRPA1‐mediated astrocytic calcium signaling is required for long‐term potentiation, while astrocytic BDNF is necessary and sufficient to support sustained synaptic plasticity.
Victor James Drew, Junsung Woo, Jung Moo Lee, Wuhyun Koh, Joungha Won, Jae‐Hun Lee, C. Justin Lee   +6 more
wiley   +1 more source

Neuromyelitis optica spectrum disorder associated with cutaneous lupus and multidrug immunosuppressant hypersensitivity. [PDF]

BMJ Case Rep
Chu Han C, Shahidatul-Adha M, Wan Hitam WH.   +2 more
europepmc   +1 more source

MRI Diffusion Tensor Image Analysis Along the Perivascular Space: Effects of Mean Tract Orientation Divergence

Journal of Magnetic Resonance Imaging, Volume 64, Issue 3, Page 815-829, September 2026.
ABSTRACT Background The diffusion tensor image analysis along the perivascular space (DTI‐ALPS) index is an established term, and ongoing research aims to explore underlying mechanisms. Hypothesis DTI‐ALPS measures are influenced by subject‐specific orientational differences of the projection and association fibers. Study Type Prospective.
Dávid Bognár, Gergely Orsi, Csirmaz Benedek, Szilvia A. Nagy, Gergely Darnai, Barnabás Dudás, Ákos Arató, Norbert Kovács, József Janszky, Gábor Perlaki   +9 more
wiley   +1 more source

Integrated Blood Inflammatory Ratios and Cerebrospinal Fluid Blood‒Brain Barrier Dysfunction Predict Relapse Risk in Neuromyelitis Optica Spectrum Disorder. [PDF]

Brain Behav
Zheng X, Shi J, Yin H, Song H, Zhai Q, Si C, Chen J, Li P, Zhang L, Li Y, Dong C, Liu H.   +11 more
europepmc   +1 more source

Advancing Thermotolerance in Beans: Integrating Physiology, Genomics, and Breeding for Climate Adaptation

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Rising global temperatures increasingly threaten bean production and the food security of millions of people who depend on these protein‐rich legumes. Heat stress during the reproductive stages induces pollen sterility, flower abscission, and disruptions in source–sink relationships, resulting in yield losses of 30%–40% or more when critical ...
Aastha Sharda, Shikha Chaudhary, Bhawna Kumari, Uday C. Jha, Mohar Singh, Inderjit Singh, Kamal Dev Sharma, Kadambot H. M. Siddique, P. V. Vara Prasad, Harsh Nayyar   +9 more
wiley   +1 more source

Satralizumab in the management of aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder during pregnancy: a case report. [PDF]

Front Immunol
Ding M, Yin B, Yao J, Liu Y, Dong H, Lu Z.   +5 more
europepmc   +1 more source