Results 51 to 60 of about 80,314 (300)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Correlation between eletrokinetic mobility and ionic dyes adsorption of Moroccan stevensite [PDF]

, 2010
This study aims at establishing a correlation between the electrical charge of Moroccan stevensite particles and ionic dyes adsorption. The electrophoretic mobility, (Ue), of the stevensite particles in water, was measured at pH 2.5–12 by ...
Amjoud, M'barek, Bouna, Lahcen, Daoudi, Lahcen, Jada, Amane, Maury, Francis, Rhouta, Benaïssa, Senocq, François   +6 more
core   +2 more sources

Aqueous Poly(arylacetylene) Dispersions [PDF]

Macromolecules, 2010
Aqueous poly(phenylacetylene) dispersions were obtained by catalytic polymerization in emulsion with a phosphine-modified Pd(II) catalyst. A range of mono- and bidentate phosphines were screened. A tBu2P(CH2)3PtBu2-modified catalyst exhibits very high rates up to 2 × 105 TO h−1 (TO = moles of monomer converted per mole of metal present in the reaction ...
Huber, Johannes, Mecking, Stefan
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Synthesis of Water-Based Dispersions of Polymer/TiO2 Hybrid Nanospheres

Nanomaterials, 2015
We develop a strategy for preparing water-based dispersions of polymer/TiO2 nanospheres that can be used to form composite materials applicable in various fields. The formed hybrid nanospheres are monodisperse and possess a hierarchical structure.
Lu Jin, Hua Wu, Massimo Morbidelli
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Photo-stability of lutein in surfactant-free lutein-zein composite colloidal particles

Food Chemistry: X, 2020
The ability of nanoparticles from the plant protein zein to protect lutein from light degradation was studied under various conditions. Lutein-zein nanoparticles were synthesized, after zein purification, by anti-solvent precipitation.
Frankjen Ynske de Boer, Arnout Imhof, Krassimir Petkov Velikov   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Glucosamine HCl-based solid dispersions to enhance the biopharmaceutical properties of acyclovir [PDF]

, 2019
The objective of the work presented here was to assess the feasibility of using glucosamine HCl as a solid-dispersion (SD) carrier to enhance the biopharmaceutical properties of a BCS class III/IV drug, acyclovir (ACV). The solid-dispersions of acyclovir
Bhagat, Snehal B., Dave, Vivek S, Patil, Arun T., Pethe, Anil M., Raut, Nishikant, Telange, Darshan R., Umekar, Milind J.   +6 more
core   +1 more source

Processable aqueous dispersions of graphene nanosheets

Nature Nanotechnology, 2008
Graphene sheets offer extraordinary electronic, thermal and mechanical properties and are expected to find a variety of applications. A prerequisite for exploiting most proposed applications for graphene is the availability of processable graphene sheets in large quantities.
Li, Dan, Müller, Marc B., Gilje, Scott, Kaner, Richard B., Wallace, Gordon G.   +4 more
openaire   +4 more sources