Results 71 to 80 of about 1,849,870 (344)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Synthesis of Water-Based Dispersions of Polymer/TiO2 Hybrid Nanospheres

Nanomaterials, 2015
We develop a strategy for preparing water-based dispersions of polymer/TiO2 nanospheres that can be used to form composite materials applicable in various fields. The formed hybrid nanospheres are monodisperse and possess a hierarchical structure.
Lu Jin, Hua Wu, Massimo Morbidelli
doaj   +1 more source

Rheological properties of aqueous dispersions of chia (Salvia hispanica L.) mucilage

, 2015
The viscoelastic and flow behavior of aqueous dispersions with different concentrations of chia mucilage (Salvia hispanica L.) from Argentina seeds was characterized.
M. Capitani, L. J. Corzo-Ríos, L. Chel-Guerrero, D. Betancur-Ancona, S. Nolasco, M. Tomás   +5 more
semanticscholar   +1 more source

Vesicle Membrane Thickness in Aqueous Dispersions of Block Copolymer Blends

, 2016
Vesicle Membrane Thickness in Aqueous Dispersions of Block Copolymer ...
Kevin P. Davis (2407297), Timothy P. Lodge (1271460), Frank S. Bates (1334340)   +2 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Photo-stability of lutein in surfactant-free lutein-zein composite colloidal particles

Food Chemistry: X, 2020
The ability of nanoparticles from the plant protein zein to protect lutein from light degradation was studied under various conditions. Lutein-zein nanoparticles were synthesized, after zein purification, by anti-solvent precipitation.
Frankjen Ynske de Boer, Arnout Imhof, Krassimir Petkov Velikov   +2 more
doaj   +1 more source

Aqueous dispersions of lipid nanoparticles wet hydrophobic and superhydrophobic surfaces

, 2018
Aqueous dispersions of food-grade lipid nanoparticles render hydrophobic and super hydrophobic surfaces wettable.
Manoj Kumar, Mayuresh A. Kulkarni, Guruswamy Kumaraswamy, Arun Banpurkar, Narendiran G. Chembu   +4 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Aqueous graphene dispersions for paper packaging

, 2022
Graphene is widely touted as the thinnest and the most versatile material available. As an atomically thin layer of carbon atoms arranged in a hexagonal configuration, graphene has a combination of technologically important properties, such as thermal ...
Zhao, Wei
core