Results 91 to 100 of about 1,287,672 (341)
Animal Models and Experimental Medicine, EarlyView.Steroid‐induced ocular hypertension is a useful mouse model for glaucoma, but published work rarely quantifies how route, dose, and schedule shape the intraocular pressure (IOP) time‐course—hindering reproducibility and forcing labs to pilot protocols.
Nicholas Y. Q. Tan +4 more
wiley +1 more source
Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes
Metabolites, 2019 (1) Background: Disruption of insulin production by native or transplanted pancreatic islets caused by auto/allo-immunity leads to hyperglycemia, a serious health condition and important therapeutic challenge due to the lifelong need for exogeneous ...
Oscar Alcazar +6 more
doaj +1 more source
Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Advanced NanoBiomed Research, EarlyView.Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
wiley +1 more source
BMC Ophthalmology, 2017 Background To measure ascorbic acid concentration in aqueous humor of patients with cataract after oral or intravenous vitamin C supplementation. Methods Forty-two eyes of 42 patients with senile cataract who underwent uncomplicated cataract surgery were
Young-Sool Hah +7 more
doaj +1 more source
Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes. [PDF]
, 2016 PurposeWe characterize aqueous angiography as a real-time aqueous humor outflow imaging (AHO) modality in cow eyes with two tracers of different molecular characteristics.MethodsCow enucleated eyes (n = 31) were obtained and perfused with balanced salt ...
Begian, Alan +10 more
core +3 more sources
Iris Damage Is Associated With Elevated Cytokine Levels in Aqueous Humor.
Investigative Ophthalmology and Visual Science, 2017 Purpose To evaluate the association between iris damage and cytokine levels in the aqueous humor (AqH). Methods A total of 201 AqH samples from 201 consecutive patients (mean age 73.7 ± 10.6) were collected at the beginning of corneal transplantation ...
Naohiko Aketa +7 more
semanticscholar +1 more source
Arthritis &Rheumatology, EarlyView.Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo +9 more
wiley +1 more source
Variation of the intraocular pressure in relation to time of death: Contribution to the determination of the true postmortem interval (PMI) [PDF]
, 2019 Introducción: La determinación del momento del fallecimiento, es un dato de singular importancia en Medicina Legal constituyendo por su complejidad en uno de los problemas que necesita evaluación objetiva en la Patología Forense.
Genero, Sebastian +3 more
core
EBOV-RNA test with RT-PCR in ocular fluids of Ebola survivors can help to safely perform cataract surgery [PDF]
, 2018 Since the Ebola virus (EBOV) was discovered in 1976, the recent 2014−2016 Ebola virus disease (EVD) outbreak in West Africa was the largest with 28,600 cases and about 11,300 deaths.
Iozzo, Nicola, Spadea, Leopoldo
core +1 more source
Aqueous Humor Dynamics: A Review [PDF]
The Open Ophthalmology Journal, 2010 Glaucoma is a family of optic neuropathies which cause irreversible but potentially preventable vision loss. Vision loss in most forms of glaucoma is related to elevated IOP with subsequent injury to the optic nerve. Secretion of aqueous humor and regulation of its outflow are physiologically important processes for maintaining IOP in the normal range.
Goel, Manik +3 more
openaire +2 more sources