Results 71 to 80 of about 1,271,022 (291)
Human aqueous humor exosomes [PDF]
Experimental Eye Research, 2015 Aqueous humor (AH) is a dynamic intraocular fluid that supports the vitality of tissues that regulate intraocular pressure. We recently discovered that extracellular nanovesicles called exosomes are a major constituent of AH. Exosomes function in extracellular communication and contain proteins and small RNA.
W. Michael Dismuke +4 more
openaire +2 more sources
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Tissue Distribution of trans-Resveratrol and Its Metabolites after Oral Administration in Human Eyes
Journal of Ophthalmology, 2017 Purpose. This study was performed to measure the concentration of trans-resveratrol and its three metabolites in human eyes. Methods. The patients who underwent pars plana vitrectomy for rhegmatogenous retinal detachment were included.
Shuaishuai Wang +7 more
doaj +1 more source
Biochemistry and Molecular Biology Education, Volume 53, Issue 2, Page 131-141, March/April 2025.Abstract In the classroom, metabolism is often approached and received as a mundane exercise in memorization. Teaching metabolism also faces the challenge of negative perceptions that can impede learning. We sought to improve the learning experience in an undergraduate lecture course on microbial metabolism by implementing an illustrated story that ...
James B. McKinlay, Katherine Kearns
wiley +1 more source
Acta Clinica CroaticaBrain-derived neurotrophic factor (BDNF) is essential for neuronal development, differentiation and survival, and aberrant BDNF expression in retina is associated with glaucoma.
Tena Križ +6 more
doaj +1 more source
The prognosis of trabeculectomy in primary angle- closure glaucoma patients [PDF]
International Journal of Ophthalmology, 2019 AIM: To evaluate whether the level of thrombospondin-1 (TSP-1) in aqueous humor can predict the prognosis of trabeculectomy in patients with primary angle-closure glaucoma (PACG).
Jun-Dong Zhu +3 more
doaj +1 more source
BMEMat, EarlyView.Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu +7 more
wiley +1 more source
Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes
Metabolites, 2019 (1) Background: Disruption of insulin production by native or transplanted pancreatic islets caused by auto/allo-immunity leads to hyperglycemia, a serious health condition and important therapeutic challenge due to the lifelong need for exogeneous ...
Oscar Alcazar +6 more
doaj +1 more source
Electronic Physician, 2017 Objective The focus of this study aimed at measuring multiple inflammatory cytokines levels in the aqueous humor of patients with primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PEXG) and senile cataract.
N. Khalef +5 more
semanticscholar +1 more source
Aqueous Humor Dynamics: A Review [PDF]
The Open Ophthalmology Journal, 2010 Glaucoma is a family of optic neuropathies which cause irreversible but potentially preventable vision loss. Vision loss in most forms of glaucoma is related to elevated IOP with subsequent injury to the optic nerve. Secretion of aqueous humor and regulation of its outflow are physiologically important processes for maintaining IOP in the normal range.
Goel, Manik +3 more
openaire +2 more sources