Results 61 to 70 of about 1,271,022 (291)

Microtopography screening to modulate the mitogenic effects of aqueous humor on human tenon fibroblasts

Frontiers in Bioengineering and Biotechnology
BackgroundGlaucoma is a leading cause of blindness, with elevated intraocular pressure being a primary risk factor due to the accumulation of aqueous humor in the anterior chamber.
Phani Krishna Sudarsanam, Nikita Konshin, Jan de Boer   +2 more
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Aqueous humor adipokine profile of primary open angle glaucoma patients and cataract patients with or without metabolic disorders [PDF]

International Journal of Ophthalmology
AIM: To investigate the role of adipokines in primary open angle glaucoma (POAG) by comparing the levels of these molecules in the aqueous humor among POAG patients and cataract patients with or without metabolic disorders.
Zi-Yao Xia, Ke Xu, Wei-Jia Zhang, De-Fu Wu, Zhe Pan, Hao-Cheng Xian, Xue-Min Li, Huai-Zhou Wang, Chun Zhang   +8 more
doaj   +1 more source

Altered by Gold: A Comparative Zooarchaeological Analysis of 19th to 20th Century Chinese and British Migrants in Ravenswood, a Northern Queensland Gold Mining Town

Archaeology in Oceania, EarlyView.
ABSTRACT Gold discoveries transformed the 19th century British colony of Queensland, Australia, driving migration, a second wave of pastoral expansion northwards, and an increasingly diverse population. This study presents a comparative and contextual zooarchaeological analysis of British and southern Chinese food waste—globally significant migrant ...
Marc Cheeseman
wiley   +1 more source

Assessment of biomarkers using multiplex assays in aqueous humor of patients with diabetic retinopathy

BMC Ophthalmology, 2017
BackgroundWith the high prevalence of type 2 diabetes, diabetic retinopathy (DR) has become a leading health problem worldwide. The pathogenesis of DR is complex and several vascular, inflammatory, and neuronal mechanisms are involved.
Hui Chen, Xiongze Zhang, Nanying Liao, F. Wen   +3 more
semanticscholar   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy

Data in Brief, 2019
This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., “Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of ...
Shuo Zhang, Christian J.F. Bertens, Roel J. Erckens, Frank J.H.M. van den Biggelaar, Tos T.J.M. Berendschot, Carroll A.B. Webers, Rudy M.M.A. Nuijts, Marlies Gijs   +7 more
doaj   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Fluorophotometric measurements of aqueous-humor flow in Filipino eyes

Philippine Journal of Ophthalmology, 2007
Objective: This study determined the rate of aqueous-humor flow in Filipino eyes. Methods: Patients were recruited from the outpatient eye clinic of the Philippine General Hospital.
George Emmanuel S.J. Comia, MD, Margarita Lat-Luna, MD, Manuel B. Agulto, MD   +2 more
doaj  

Aqueous Angiography in Living Non-Human Primates Show Segmental, Pulsatile, and Dynamic Angiographic Aqueous Humor Outflow

Ophthalmology (Rochester, Minn.), 2017
Purpose To evaluate the feasibility of safely performing aqueous angiography in intact eyes of living non-human primates (NHPs) for evaluating aqueous humor outflow and segmental patterns. Methods Aqueous angiography was performed in 6 non-human primates.
A. Huang, M. Li, Di-ya Yang, Huai-zhou Wang, Ningli Wang, R. Weinreb   +5 more
semanticscholar   +1 more source