Results 51 to 60 of about 687,129 (240)
Aqueous humor adipokine profile of primary open angle glaucoma patients and cataract patients with or without metabolic disorders [PDF]
International Journal of OphthalmologyAIM: To investigate the role of adipokines in primary open angle glaucoma (POAG) by comparing the levels of these molecules in the aqueous humor among POAG patients and cataract patients with or without metabolic disorders.
Zi-Yao Xia +8 more
doaj +1 more source
PLoS ONE, 2020 Alzheimer's disease (AD) is an ageing-related neurodegenerative disease characterized and diagnosed by deposition of insoluble amyloid-β (Aβ) plaques in the brain.
Da Eun Kwak +8 more
doaj +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
Advanced Science, EarlyView.By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
Beyond Probiotics: Postbiotics for Healthy Aquaculture
Advanced Science, EarlyView.This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas +12 more
wiley +1 more source
Data in Brief, 2019 This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., “Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of ...
Shuo Zhang +7 more
doaj +1 more source
Advanced Science, EarlyView.An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He +6 more
wiley +1 more source
Fluorophotometric measurements of aqueous-humor flow in Filipino eyes
Philippine Journal of Ophthalmology, 2007 Objective: This study determined the rate of aqueous-humor flow in Filipino eyes. Methods: Patients were recruited from the outpatient eye clinic of the Philippine General Hospital.
George Emmanuel S.J. Comia, MD +2 more
doaj
Advanced Science, EarlyView.Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing +9 more
wiley +1 more source
Acta Clinica CroaticaBrain-derived neurotrophic factor (BDNF) is essential for neuronal development, differentiation and survival, and aberrant BDNF expression in retina is associated with glaucoma.
Tena Križ +6 more
doaj +1 more source
Tissue Distribution of trans-Resveratrol and Its Metabolites after Oral Administration in Human Eyes
Journal of Ophthalmology, 2017 Purpose. This study was performed to measure the concentration of trans-resveratrol and its three metabolites in human eyes. Methods. The patients who underwent pars plana vitrectomy for rhegmatogenous retinal detachment were included.
Shuaishuai Wang +7 more
doaj +1 more source