Results 221 to 230 of about 54,125 (306)

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen   +12 more
wiley   +1 more source

iPSC-derived ITGA6-positive cells restore aqueous humor outflow in glaucoma eyes. [PDF]

open access: yesNat Commun
Feng P   +25 more
europepmc   +1 more source

The Circadian Transcription Factor CLOCK Modulates Oxidative Stress Resistance via the ACHL–Relish Axis in Drosophila

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
This study identifies the circadian transcription factor CLOCK (CLK) as a key regulator of oxidative stress resistance in fruit flies. CLK controls immune responses by driving rhythmic transcription of an RNA‐binding protein‐Achilles (ACHL) in the fly brain, which post‐transcriptionally represses the NF‐κB homolog Relish, limiting immune activation and
Xu Liu   +7 more
wiley   +1 more source

Altered High-Density Lipoprotein Expression Pattern in the Aqueous Humor From Eyes With Age-Related Macular Degeneration. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Kramer A   +8 more
europepmc   +1 more source

The Role of Phosphoinositides in Aqueous Humor Dynamics via Optogenetic Stimulation in the Trabecular Meshwork

open access: green, 2019
Jorge A. Alvarado   +6 more
openalex   +1 more source

Visual Assessment of Aqueous Humor Outflow

open access: diamond, 2019
Xiaobin Xie   +4 more
openalex   +1 more source

Intermittent Fasting Alleviates Anesthesia/Surgery‐Induced Delirium‐Like Behavior in Aged Mice by Remodeling Gut Microbiota

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Preoperative intermittent fasting alleviates postoperative delirium‐like behaviors in aged mice by remodeling gut microbiota and preserving shortchain fatty acids. This gut‐brain interaction maintains hippocampal mitochondrial dynamics and synaptic plasticity, offering a promising non‐pharmacological strategy for perioperative neuroprotection. ABSTRACT
Peiying Huang   +9 more
wiley   +1 more source

Lymphatic characteristics of the outflow tract of aqueous humor: An anatomical study in humans. [PDF]

open access: yesSaudi J Ophthalmol
Kakizaki H   +6 more
europepmc   +1 more source

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