Results 31 to 40 of about 54,125 (306)

Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases

open access: yesNanomaterials, 2018
Emerging roles of exosomes in the pathogenesis of major blindness-threatening diseases, such as age-related macular degeneration, glaucoma, and corneal dystrophy, were discovered by aqueous humor analysis.
Min-Yen Hsu   +8 more
doaj   +1 more source

Age-related changes of vitamin C levels in aqueous humour [PDF]

open access: yesVojnosanitetski Pregled, 2015
Background/Aim. Age-related cataract is a common disease among senior population. Vitamin C is the most effective reducing hydrosoluble antioxidant causing reduction in the levels of free radicals in crystaline lens. The aim of this study was to
Čanadananović Vladimir   +4 more
doaj   +1 more source

The intraocular pressure response to dehydration: a pilot study [PDF]

open access: yes, 2011
This study was designed to determine the Intraocular Pressure (IOP) response to differing levels of dehydration. Seven males participated in a 90 minute treadmill walk (5 km/h and 1 % grade) in both a cool (22 °C) and hot (43 °C) climate. At Baseline and
Feigl, Beatrix   +2 more
core   +2 more sources

NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression

open access: yesCell Reports, 2021
Summary: Anterior segment dysgenesis is often associated with cornea diseases, cataracts, and glaucoma. In the anterior segment, the ciliary body (CB) containing inner and outer ciliary epithelia (ICE and OCE) secretes aqueous humor that maintains ...
Ji Pang   +17 more
doaj   +1 more source

All TIEd up: mechanisms of Schlemm's canal maintenance. [PDF]

open access: yes, 2017
Glaucoma is a leading cause of blindness, with an estimated world-wide prevalence of 3.5% in members of the population older than 40 years of age. Elevated intraocular pressure as the result of abnormal resistance to aqueous humor drainage is a major ...
Jeremiah Bernier-Latmani   +2 more
core   +1 more source

Matrix Metalloproteinases and Glaucoma Treatment. [PDF]

open access: yes, 2020
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed   +3 more
core  

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes. [PDF]

open access: yes, 2016
PurposeWe characterize aqueous angiography as a real-time aqueous humor outflow imaging (AHO) modality in cow eyes with two tracers of different molecular characteristics.MethodsCow enucleated eyes (n = 31) were obtained and perfused with balanced salt ...
Begian, Alan   +10 more
core   +3 more sources

Distinctive and pervasive alterations in aqueous humor protein composition following different types of glaucoma surgery [PDF]

open access: yes, 2015
PURPOSE: To investigate whether specific glaucoma surgeries are associated with differences in aqueous humor protein concentrations compared to eyes without filters.
Lai, Xianyin   +4 more
core   +1 more source

Novel Characterization and Live Imaging of Schlemm's Canal Expressing Prox-1 [PDF]

open access: yes, 2014
Schlemm's canal is an important structure of the conventional aqueous humor outflow pathway and is critically involved in regulating the intraocular pressure.
Chen, Lu   +3 more
core   +7 more sources

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

open access: yesAdvanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao   +11 more
wiley   +1 more source

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