Results 131 to 140 of about 10,969 (168)
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Arachidonate 12-lipoxygenase of porcine leukocyte with activity for 5-hydroxyeicosatetraenoic acid
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1982When arachidonic acid was incubated with porcine polymorphonuclear leukocytes, 12-hydroxy-5,8,10,14-eicosatetraenoic acid was produced as a major product. The production of this compound was not accounted for by contaminating platelets known to contain arachidonate 12-lipoxygenase. The enzyme was found predominantly in a cytosol fraction of leukocytes,
T, Yoshimoto +3 more
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Stimulation by carrageenan of arachidonate 12-lipoxygenase activity in dog gingival tissue
Archives of Oral Biology, 1991At 4 h after injection of carrageenan into the gingiva, the 12-lipoxygenase activity of the gingival homogenate was markedly increased. Activity in the cytosol and microsomal fractions was markedly increased when assessed as the specific activity based on nmol/min/mg of protein, and in the cytosol fraction as the percentage distribution of total ...
K, Tamai +5 more
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Tissue Distribution and Subcellular Localization of Platelet-Type Arachidonate 12-Lipoxygenase
1997Arachidonate 12-lipoxygenase introduces one oxygen molecule regiospecifically and stereoselectively into the carbon 12 of arachidonic acid. Our group has demonstrated the occurrence of two isoforms of 12-lipoxygenase (platelet-type and leukocyte-type) which were distinguished in terms of substrate specificity, the cross-reactivity of their antibodies ...
M, Nakamura +5 more
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Docking arachidonic acid into human 5/12-lipoxygenase using ICM
2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW), 2011Lipoxygenases(LOX) are a super gene family of iron-containing enzymes, that catalyze the stereo- and regio-specific formation of fatty acid hydroperoxides from polyunsaturated fatty acids. Mammalian lipoxygenase have been implicated in the pathogenesis of various inflammatory responses.
null Mingmin Bai +2 more
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Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet beta-cells
American Journal of Physiology-Endocrinology and Metabolism, 1992The immunohistochemical distribution of arachidonate lipoxygenases in rat pancreas was characterized with specific polyclonal anti-5-lipoxygenase and anti-12-lipoxygenase antibodies. Immunohistochemical analysis of formaldehyde-fixed paraffin-embedded rat pancreas using anti-12-lipoxygenase antibody and biotin-avidin-peroxidase detection demonstrated ...
V R, Shannon +3 more
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Journal of Lipid Mediators and Cell Signalling, 1995
T, Yoshimoto, S, Yamamoto
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T, Yoshimoto, S, Yamamoto
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BglII RFLP at the porcine arachidonate 12‐lipoxygenase (LOG12) locus
Animal Genetics, 1994M B, Coscelli +3 more
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