Arachidonate lipoxygenases - Open Access .click

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Novel n-3 Immunoresolvents: Structures and Actions [PDF]

, 2014
Resolution of inflammation is now held to be an active process where autacoids promote homeostasis. Using functional-metabololipidomics and in vivo systems, herein we report that endogenous n-3 docosapentaenoic (DPA) acid is converted during inflammation-
Colas, Romain A., Dalli, Jesmond, Serhan, Charles N. +2 more
core +1 more source

Methyl jasmonate and cis jasmone induce apoptosis in Pc-3 and LncaP prostate cancer lines

, 2005
Methyl jasmonate (MJ) and cis jasmone (CJ), lipid-derived plant stress hormones, were studied for their effects against both hormone dependent (LNCaP) and hormone independent (PC3) human prostate cancer cell lines. Both 2 mM MJ or CJ inhibited the growth
Bathina, Madhavi
core +1 more source

THE INFLUENCE OF QUERCETIN CONCENTRATION ON ITS INTERMOLECULAR INTERACTION WITH SOYBEAN LIPOXYGENASE-1 [PDF]

, 2008
As research studies on lipoxygenase inhibition indicate quercetin as a one of the most potent inhibitors of this enzyme, this work presents our results concerning the inhibition of soybean lipoxygease-1 by pure quercetin.
Chedea, Veronica S. +3 more
core +2 more sources

Molecular dynamics study on the Apo- and Holo-forms of 5-lipoxygenase [PDF]

, 2017
Lipoxygenases (LOXs) are nonheme iron-containing enzymes catalyzing the dioxygenation of polyunsaturated fatty acids. LOX catalytic activity depends on the presence of iron in the active site and the iron removal is also able to affect the membrane ...
Enrico, Dainese, Maccarrone, Mauro, Torras Costa, Juan +2 more
core +2 more sources

Hypoxia and lipid signaling [PDF]

, 2017
Sufficient oxygen supply is crucial for the development and physiology of mammalian cells and tissues. When simple diffusion of oxygen becomes inadequate to provide the necessary flow of substrate, evolution has provided cells with tools to detect and ...
Huwiler, Andrea, Pfeilschifter, Josef
core

Arachidonate 15-Lipoxygenase [PDF]

, 2020
openaire +1 more source

Heart failure–induced activation of phospholipase iPLA2γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore [PDF]