Results 201 to 210 of about 104,843 (319)

MBOAT7 encephalopathy: Characterizing the neurology and epileptology

Epilepsia, EarlyView.
Abstract Objective Biallelic pathogenic MBOAT7 variants are associated with neurodevelopmental disorders, intellectual disability (ID), epilepsy, and neuropsychiatric disorders such as attention‐deficit/hyperactivity disorder and autism spectrum disorders. We aimed to characterize the epilepsy phenotype in a cohort of patients affected by this syndrome.
Sebastian Ortiz De la Rosa, Valentina Rizzo, Robin‐Tobias Jauss, Tobias Bartolomaeus, Maria Escolar, Geneviève Bernard, Ralitza Gavrilova, Rebecca Ahrens‐Nicklas, Gabrielle Lemire, Kym M. Boycott, Saadet Mercimek‐Andrews, Paolo Prontera, Cinzia Costa, Bojana Rakic, Cornelius F. Boerkoel, Stephanie Huynh, Linda Huh, Elliott Sherr, Emanuela Argilli, Juan Darío Ortigoza‐Escobar, Didac Casas‐Alba, Tania Nunes, David A. Koolen, Konrad Platzer, Marianne S. Khinchi, Elena Gardella, Christina D. Fenger, Rikke S. Møller, Allan Bayat   +28 more
wiley   +1 more source

FAHD1 and mitochondrial metabolism: a decade of pioneering discoveries

The FEBS Journal, EarlyView.
This paper reviews a decade of research on FAHD1, an important yet underappreciated enzyme in mitochondrial metabolism. FAHD1 plays a crucial role in energy production, oxidative stress regulation, and processes related to aging and overall health.
Elia Cappuccio, Max Holzknecht, Michèle Petit, Anne Heberle, Yana Rytchenko, Athanasios Seretis, Ciro L. Pierri, Hubert Gstach, Pidder Jansen‐Dürr, Alexander K. H. Weiss   +9 more
wiley   +1 more source

A carbon-centered free radical intermediate in the prostaglandin synthetase oxidation of arachidonic acid. Spin trapping and oxygen uptake studies.

, 1980
Ronald P. Mason, B. Kalyanaraman, Beth Tainer, Thomas E. Eling   +3 more
openalex   +1 more source

The inhibitory effects of BW 755C on arachidonic acid metabolism in human polymorphonuclear leukocytes [PDF]

, 1980
Olof Rádmark, Curt Malmsten, Bengt Samuelsson   +2 more
openalex   +1 more source

LPCAT3 regulates the proliferation and metastasis of serous ovarian cancer by modulating arachidonic acid. [PDF]

Transl Oncol
Wen F, Ling H, Ran R, Li X, Wang H, Liu Q, Li M, Yu T.   +7 more
europepmc   +1 more source

A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains

The FEBS Journal, EarlyView.
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley   +1 more source

Phosphorylation of distal C-terminal residues promotes TRPV4 channel activation in response to arachidonic acid. [PDF]

J Biol Chem
Parthasarathy A, Anishkin A, Xie Y, Drachuk K, Nishijma Y, Fang J, Koukouritaki SB, Wilcox DA, Zhang DX.   +8 more
europepmc   +1 more source

Release and metabolism of arachidonic acid in human neutrophils.

, 1981
Christopher Walsh, B. Moseley Waite, Michaël Thomas, Lawrence R. DeChatelet   +3 more
openalex   +1 more source

Natural aminosterols inhibit NMDA receptors with low nanomolar potency

The FEBS Journal, EarlyView.
Misfunction of N‐methyl‐D‐aspartate (NMDA) receptors is associated with many brain disorders, making them primary targets for drug discovery. Trodusquemine and other natural aminosterols inhibit NMDA receptors with low nanomolar potency through binding to the cell membranes followed by interaction with the channels.
Giulia Fani, Elisabetta Coppi, Silvia Errico, Federica Cherchi, Martina Gennari, Denise Barbut, Michele Vendruscolo, Michael Zasloff, Anna Maria Pugliese, Fabrizio Chiti   +9 more
wiley   +1 more source

Effects of Salmonella Typhimurium infection on intestinal flora and intestinal tissue arachidonic acid metabolism in Wenchang chickens. [PDF]

Front Microbiol
Chen S, Xie Y, Guo D, Li T, Tan Z, Ran X, Wen X.   +6 more
europepmc   +1 more source