Results 281 to 290 of about 104,843 (319)

Gut microbiota of miR-30a-5p-deleted mice aggravate high-fat diet-induced hepatic steatosis by regulating arachidonic acid metabolic pathway. [PDF]

Clin Transl Med
Wang R, Zhang X, Wang Y, Lin Y, Zhou Y, Wang Y, Li G.   +6 more
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An adaptable in silico ensemble model of the arachidonic acid cascade.

Mol Omics
Uttley M, Horne G, Tsigkinopoulou A, Del Carratore F, Hawari A, Kiezel-Tsugunova M, Kendall AC, Jones J, Messenger D, Bhogal RK, Breitling R, Nicolaou A.   +11 more
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Arachidonic Acid Derivatives and Neuroinflammation

CNS & Neurological Disorders - Drug Targets, 2022
: Neuroinflammation is characterized by dysregulated inflammatory responses localized within the brain and spinal cord. Neuroinflammation plays a pivotal role in the onset of several neurodegenerative disorders and is considered a typical feature of these disorders.
Gorica, Era, Calderone, Vincenzo
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ARACHIDONIC ACID METABOLISM

Annual Review of Biochemistry, 1986
C YC LOO XYGENASE PRODUC TS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . 70 Prostaglandin Endoperoxide Synthase 70 Metabolism of the Prostaglandin Endoperoxides 71 P RODUC TS OF THE 12-LIPO XYGEN ASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Aubrey R. Morrison, John Turk, Philip Needleman, B A Jakschik, J B Lefkowith   +4 more
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Prostaglandins, Arachidonic Acid, and Inflammation

Science, 1980
The enzymatic oxidation of arachidonic acid has been shown to yield potent pathological agents by two major pathways. Those of the prostaglandin (PG) pathway, particularly PGE2, have been implicated as inflammatory mediators for many years. The discovery and biological activities of thromboxane A2and prostacyclin as well as a destructive oxygen ...
Frederick A. Kuehl, Robert W. Egan
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Arachidonic acid metabolism

Preventive Medicine, 1987
Arachidonic acid metabolites can act as tumor promoters and can affect growth and metastases of tumors in three ways: (a) Prostacyclin inhibits and thromboxane facilitates platelet-tumor cell interactions and, thereby, tumor cell invasiveness; (b) the cytoprotective action of prostaglandins contributes to epithelial cell integrity and influences tissue
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Arachidonic acid production by microorganisms

Biotechnology and Applied Biochemistry, 1992
Arachidonic acid (AA) is a natural precursor of prostaglandins, thromboxanes, leukotrienes, prostacyclins, and a large group of C20 compounds which are of intrinsic medical interest. At present, the only source of AA is animal tissues. However, it is present in several microorganisms. This review describes the production of AA by microorganisms and its
Pratima Bajpai, Pramod K. Bajpai
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CHEMIEXCITATION IN THE ARACHIDONIC ACID CASCADE

Photochemistry and Photobiology, 1991
Abstract—As investigated in neutrophils, the very weak luminescence accompanying the arachidonic acid cascade is associated with the lipoxygenase pathway. The emission is dramatically enhanced by energy transfer to chlorophylla. The number of chlorophyll molecules excited to the fluorescent state per oxygen consumed, (the S1/O2ratio), equal to the ...
Ana L. T. O. Nascimento, Giuseppe Cilento   +1 more
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Arachidonic acid aggregates neutrophils

Inflammation, 1979
Arachidonic acid, but not several structurally similar fatty acids, stimulated neutrophils in suspension to aggregate; this effect was blocked by 5, 8, 11, 14-eicosatetraynoic acid, an inhibitor of arachidonic acid metabolism. Analagous to platelets, arachidonate may be a precursor of active metabolites which mediate neutrophil responses.
Elmer L. Becker, Peter A. Ward, H. S. Showell, J. T. O'Flaherty   +3 more
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