Results 151 to 160 of about 128,801 (345)

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Spatial mapping of PUFA incorporation into phospholipids with bisallylic deuteration

open access: yesJournal of Lipid Research
MS imaging using stable isotope-labeled fatty acids provides a groundbreaking approach to precisely localizing exogenous fatty acids and their metabolites in vivo.
Junji Obi   +5 more
doaj   +1 more source

Research Progress on Upper Airway Cough Syndrome

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Insights into the fatty acid profile and taxonomy of the extremophilic moss Hedwigia emodica (Bryophyta, Hedwigiales, Hedwigiaceae)

open access: yesLilloa
Extremophilic mosses are known to produce a variety of long-chain polyunsaturated fatty acids in response to various abiotic stresses. These fatty acids facilitate in membrane fluidity, enabling their survival in extreme conditions.
Anshul Dhyani   +3 more
doaj   +1 more source

Crystal structure and functional characterization of an Asp49 phospholipase A2 from the bushmaster (Lachesis muta)

open access: yesActa Crystallographica Section F, EarlyView.
The crystal structure of an Asp49 phospholipase A2 from L. muta is reported, revealing a tetrameric assembly, catalytic conservation and a polarized electrostatic surface potentially linked to membrane targeting.Snake‐venom phospholipases A2 (PLA2s) are small, structurally conserved enzymes that contribute significantly to the pathophysiology of ...
Noelia Erika Neyra Chama   +9 more
wiley   +1 more source

Heart failure–induced activation of phospholipase iPLA2γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore [PDF]

open access: yes, 2018
Cedars, Ari M.   +8 more
core   +2 more sources

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