Results 171 to 180 of about 5,117,744 (378)

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

Insights into the fatty acid profile and taxonomy of the extremophilic moss Hedwigia emodica (Bryophyta, Hedwigiales, Hedwigiaceae)

open access: yesLilloa
Extremophilic mosses are known to produce a variety of long-chain polyunsaturated fatty acids in response to various abiotic stresses. These fatty acids facilitate in membrane fluidity, enabling their survival in extreme conditions.
Anshul Dhyani   +3 more
doaj   +1 more source

Cold atmospheric plasma combined with nanoparticles in cancer therapy

open access: yesInterdisciplinary Medicine, EarlyView.
Cold atmospheric plasma (CAP) generates a range of reactive oxygen and nitrogen species (RONS), including singlet oxygen (1O2), hydrogen peroxide (H2O2), hydroxyl radicals (·OH), nitrate (NO3− ${{\text{NO}}_{3}}^{-}$), and nitrite (NO2− ${{\text{NO}}_{2}}^{-}$), which induce oxidative stress and apoptosis in cancer cells.
Yunhao Wang   +7 more
wiley   +1 more source

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang   +4 more
wiley   +1 more source

D-4F-mediated reduction in metabolites of arachidonic and linoleic acids in the small intestine is associated with decreased inflammation in low-density lipoprotein receptor-null mice

open access: yesJournal of Lipid Research, 2012
To test the hypothesis that intestine is a major site of action for D-4F, LDLR−/− mice were fed a Western diet (WD) and administered the peptide subcutaneously (SQ) or orally.
Mohamad Navab   +6 more
doaj  

Evaluation of Function and Biochemical Parameters of Platelet Concentrates (PCs) Prepared From Blood Donors With a History of COVID‐19 During the Platelet Storage

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background COVID‐19 can affect hematological and biochemical parameters, potentially altering platelet function. This study aimed to evaluate the long‐term effects of COVID‐19 on the quality of platelet concentrates (PCs) collected from donors with a history of infection.
Fatemeh Arastehnazar   +4 more
wiley   +1 more source

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