Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve +5 more
wiley +1 more source
Integrated Transcriptomic and Metabolomic Analysis of the Mechanism of Intramuscular Fat Differences in Wandong Cattle. [PDF]
He F +8 more
europepmc +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Tumoral ALOX5 mediated arachidonic acid metabolism regulates immune response in non-small cell lung cancer. [PDF]
Gao Y +10 more
europepmc +1 more source
Fatty acid profiles in blood and tissues of parenteral nutrition-fed neonatal piglets using a novel lipid emulsion containing choline. [PDF]
Pauline ML +11 more
europepmc +1 more source
Caffeine in cerebrovascular research: To withdraw or not to withdraw?
Experimental Physiology, EarlyView.
Brooke R. Shepley +2 more
wiley +1 more source
Effects of alfalfa fermented feed on growth performance, meat quality, and fecal microflora of Taoyuan Black pigs. [PDF]
Zhu Y +11 more
europepmc +1 more source
Effect of nicardipine and amlodipine on the brain free arachidonic acid level in hypoxic rats
Gordana Župan +5 more
openalex +1 more source
Alterations of Bioactive Lipid Profiles in the Retina Following Traumatic Optic Neuropathy in Mice. [PDF]
Kim MY +6 more
europepmc +1 more source

