Food Frontiers, Volume 7, Issue 1, January 2026.ABSTRACT Gastrointestinal diseases remain a significant global health concern, primarily due to the limitations of current pharmacological treatments, which often come with adverse side effects and high recurrence rates. This situation highlights the urgent need for safer and more effective alternatives.
Isabel Sousa Alcântara +7 more
wiley +1 more source
Preparation, physicochemical properties, and immunomodulatory activity of glycoproteins from Syngnathoides biaculeatus. [PDF]
Nat Prod BioprospectXia X +7 more
europepmc +1 more source
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
Medicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca +2 more
wiley +1 more source
Causal Relationship Between Metabolic Traits and Risk of NSCLC: A Two-Sample Mendelian Randomization Analysis. [PDF]
J CancerLi X, Cui W, Duan C, Zhang C.
europepmc +1 more source
Brain Pathology, Volume 36, Issue 1, January 2026.Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li +7 more
wiley +1 more source
Low-dose radiation and malathion co-exposure instigates long-term neurological sequelae and synergistic disruption of lipid homeostasis and energy metabolism in the hippocampus. [PDF]
Sci RepNarasimhamurthy RK +7 more
europepmc +1 more source
Dendritic Cell Migration: An Essential Step in Initiating Adaptive Immunity Across Tissues
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT Immune surveillance of tissues is primarily carried out by dendritic cells (DCs), which act as sentinels for the adaptive immune system. To accomplish this task, DCs migrate from tissues to regional lymph nodes, or from blood‐exposed regions of the spleen to the white pulp, to prime T cell responses. DC migration is a tightly regulated process
Eli C. Olson +2 more
wiley +1 more source
Dietary hydrolysable tannin improves intestinal health of largemouth bass (Micropterus salmoides): insights from NF-κB signaling pathway and arachidonic acid metabolism. [PDF]
J Anim Sci BiotechnolYang M +11 more
europepmc +1 more source
Mechanosensing in Dendritic Cells
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT Since their discovery, dendritic cells have been recognized for their unusual capacity to sense and respond to physical stimuli within their environment. However, it took nearly two decades—and the advent of mechanobiology—to elucidate the underlying mechanisms and functional implications of this mechanical hypersensitivity. In this review, we
Vincent Calmettes +5 more
wiley +1 more source
Pharmacovigilance‐Based Identification and Mechanistic Exploration of Periodontitis‐Related Drugs
Journal of Clinical Periodontology, Volume 53, Issue 1, Page 117-126, January 2026.ABSTRACT Background Periodontitis is a common chronic inflammatory disease. However, drug‐related risks and underlying molecular mechanisms remain underexplored from large real‐world data. Methods We first mined the US Food and Drug Administration Adverse Event Reporting System (FAERS) database to identify drugs disproportionately associated with ...
Wuda Huoshen +11 more
wiley +1 more source