Results 271 to 280 of about 77,615 (306)
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CHEMIEXCITATION IN THE ARACHIDONIC ACID CASCADE
Photochemistry and Photobiology, 1991Abstract—As investigated in neutrophils, the very weak luminescence accompanying the arachidonic acid cascade is associated with the lipoxygenase pathway. The emission is dramatically enhanced by energy transfer to chlorophylla. The number of chlorophyll molecules excited to the fluorescent state per oxygen consumed, (the S1/O2ratio), equal to the ...
A L, Nascimento, G, Cilento
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Vasoactivity of arachidonic acid epoxides
European Journal of Pharmacology, 1987Arachidonic acid (AA) can be metabolized to epoxides and their corresponding diols via the cytochrome P450 epoxygenase pathway. We have compared the vascular activity of four synthetically prepared epoxyeicosatrienoic acids, i.e. 5,6-, 8,9-, 11,12- and 14,15-EET (2-20 microM) on the isolated perfused rat tail artery.
M A, Carroll +4 more
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Regulation and metabolism of arachidonic acid
Clinical Reviews in Allergy & Immunology, 1999The metabolism of AA reflects a carefully balanced series of biochemical pathways. The level of free arachidonate in a cells is controlled by de novo synthesis, dietary uptake, and transcellular metabolism. Lysophospholipids are key controlling substrates for a variety of acyl transferase and transacylase reactions, whose combined effect is to remodel ...
M C, Seeds, D A, Bass
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Psoriasis and the arachidonic acid cascade
Journal of Dermatological Science, 1999Arachidonic acid (5.8,11,14-eicosatetraenoic acid C20:4, n-6) is released from the cell membrane by the action of phospholipases on membrane phospholipids. Metabolites of arachidonic acid, which are generically termed eicosanoids, including prostaglandins, thromboxane, leukotrienes and hydroxyeicosatetraenoic acids, have been implicated as mediators or
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Prostaglandins, Arachidonic Acid, and Inflammation
Science, 1980The enzymatic oxidation of arachidonic acid has been shown to yield potent pathological agents by two major pathways. Those of the prostaglandin (PG) pathway, particularly PGE2, have been implicated as inflammatory mediators for many years. The discovery and biological activities of thromboxane A2and prostacyclin as well as a destructive oxygen ...
F A, Kuehl, R W, Egan
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Biologic Importance of Arachidonic Acid
Archives of Internal Medicine, 1981The most abundant prostaglandin precursor is arachidonic acid (or its precursor, linoleic acid). The isolation and identification of prostaglandin compounds in a particular tissue, knowledge of the biologic properties of these compounds, and the use of readily available inhibitors of the prostaglandin pathway by aspirin-like drugs constitute the main ...
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Metabolism of Arachidonic Acid
Annals of the New York Academy of Sciences, 1988S, Moncada, E A, Higgs
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Metabolites of arachidonic acid
Clinical Reviews in Allergy, 1983W F, Stenson, C W, Parker
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