Results 61 to 70 of about 6,673 (263)
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Revista Vasca de Administración Pública, 2009 The prohibition of arbitrariness, the duty to give reasons and the duty to justify decisions have become principles of main relevance in the judicial control of administrative discretion.
Eva Desdentado Daroca
doaj +1 more source
Reference in Formal Semantics and Natural Language: A Methodological Route
Phenomenology and Mind, 2019 In this paper, I will tackle the notion of reference of singular terms in the light of a classic analytic divide, i.e. whether its analysis, like the analysis of other basic notions, should be carried out in natural language or in the semantics of formal
Francesca Boccuni
doaj +1 more source
Towards a Theory of Arbitrary Law-making in Migration Policy
Etikk i Praksis: Nordic Journal of Applied Ethics, 2020 The article considers what arbitrary law-making is and what may count as arbitrary law-making in the field of migration policy. It contributes to the discussion of arbitrary law-making in relation to migration policy in two ways.
Patricia Mindus
doaj +1 more source
Advances in Applied Mathematics, 2008 A matching in a group G is a bijection f from a subset A to a subset B in G such that af(a) does not belong to A for all a in A. The group G is said to have the matching property if, for any finite subsets A,B in G of same cardinality with B avoiding 1, there is a matching from A to B.
Shalom Eliahou, Cédric Lecouvey
openaire +3 more sources
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Features of attention and memory of students – generation Z in the context of digitalization
Вестник Мининского университетаIntroduction. The modern information world has made adjustments to the development of cognitive functions of generations. Many researchers have noted a decrease in memory, attention, and thinking abilities. To a lesser extent, the attention of generation
V. I. Pishchik, G. A. Molokhina
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source