Results 81 to 90 of about 13,694 (297)

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Testing the cognitive burden of two choice modeling valuation variants. The between and within sample approaches [PDF]

open access: yes
Scores are commonly used in environmental valuation exercises. The two main procedures when testing for score differences are the within sample and the between sample approaches. Their conclusions do not always coincide.
Pierre-Alexandre Mahieu   +2 more
core  

The egalitarian case for open borders:moral arbitrariness [PDF]

open access: yes
This paper argues that recent debates on egalitarian objections to immigration restrictions overlook a crucial, powerful normative principle that underpins objections to inequalities: any inequalities between morally equal persons – whether in goods ...
Hillier-Smith, Bradley
core   +1 more source

Parametrising arbitrary constructions [PDF]

open access: yesProbus, 2018
AbstractThis article aims to reconsider some restrictions on the distribution of of the arbitrarysi/sein Romance. The main theoretical tenet of the work is that the observed cross-linguistic variation results from a set of micro-parameters ruling the merging site ofsi/seand the agree relations occurring betweensi/seand probing elements such as v and T.
openaire   +2 more sources

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

An introduction to and commentary on Luis J. Prieto’s “A semiology: Problems and routes”

open access: yesSign Systems Studies
The following notes are a commentary on Luis J. Prieto’s text “A semiology: Problems and routes”, an English translation of “Une sémiologie: problems et parcours”.
E. I. Chávez Barreto
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Arbitrariness

open access: yes, 2012
Bakalaura darbā aplūkots Krimināllikuma 279.pantā paredzētais noziedzīgais nodarījums patvarība. Bakalaura darba mērķis ir noskaidrot būtiskākās problēmas patvarības kā noziedzīga nodarījuma kvalifikācijā, pētot doktrīnu, normatīvo regulējumu un tiesu ...
Vilde, Elīna
core  

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir   +2 more
wiley   +1 more source

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