Results 71 to 80 of about 112,166 (340)

High proportions of bacteria and archaea across most biomes remain uncultured

The ISME Journal, 2019
A recent paper by Martiny argues that “high proportions” of bacteria in diverse Earth environments have been cultured. Here we reanalyze a portion of the data in that paper, and argue that the conclusion is based on several technical errors, most notably
A. D. Steen, A. Crits-Christoph, P. Carini, Kristen M. DeAngelis, Kristen M. DeAngelis, Noah Fierer, Noah Fierer, K. Lloyd, J. C. Thrash   +8 more
semanticscholar   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Ammonia Oxidation by the Arctic Terrestrial Thaumarchaeote Candidatus Nitrosocosmicus arcticus Is Stimulated by Increasing Temperatures

Frontiers in Microbiology, 2019
Climate change is causing arctic regions to warm disproportionally faster than those at lower latitudes, leading to alterations in carbon and nitrogen cycling, and potentially higher greenhouse gas emissions.
Ricardo J. Eloy Alves, Melina Kerou, Anna Zappe, Anna Zappe, Romana Bittner, Sophie S. Abby, Heiko A. Schmidt, Kevin Pfeifer, Kevin Pfeifer, Christa Schleper   +9 more
doaj   +1 more source

Size-fractionated microbiome observed during an eight-month long sampling in Jiaozhou Bay and the Yellow Sea

Scientific Data, 2022
Measurement(s) temperature of seawater • salinity of seawater • chlorophyll a • particulate organic carbon (POC) of seawater • dissolved organic carbon (DOC) of seawater • total nitrogen (TN) of seawater • total nitrate of seawater • nitrite of seawater •
Jianchang Tao, Wenxiu Wang, J L Weissman, Yongyu Zhang, Songze Chen, Yuanqing Zhu, Chuanlun Zhang, Shengwei Hou   +7 more
doaj   +1 more source

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source

Identification of XylR, the Activator of Arabinose/Xylose Inducible Regulon in Sulfolobus acidocaldarius and Its Application for Homologous Protein Expression

Frontiers in Microbiology, 2020
The thermophilic archaeon Sulfolobus acidocaldarius can use different carbon sources for growth, including the pentoses D-xylose and L-arabinose. In this study, we identified the activator XylR (saci_2116) responsible for the transcriptional regulation ...
Nienke van der Kolk, Alexander Wagner, Alexander Wagner, Michaela Wagner, Michaela Wagner, Bianca Waßmer, Bettina Siebers, Sonja-Verena Albers   +7 more
doaj   +1 more source

Asgard archaea capable of anaerobic hydrocarbon cycling

Nature Communications, 2019
Large reservoirs of natural gas in the oceanic subsurface sustain complex communities of anaerobic microbes, including archaeal lineages with potential to mediate oxidation of hydrocarbons such as methane and butane. Here we describe a previously unknown
K. Seitz, Nina Dombrowski, Laura Eme, A. Spang, Jonathan Lombard, J. Sieber, A. Teske, Thijs J. G. Ettema, B. Baker   +8 more
semanticscholar   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

Advanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang, Hexing Han, Yufeng Liu, Zhiyuan Ning, Yujie Ma, Haidan Wang, Jinling Xu, Qiansheng Huang, Wenjuan Cui, Yuanchun Zhou, Yang Gao, Bin Wang, Yi Du   +12 more
wiley   +1 more source

Electron cryo-microscopy reveals the structure of the archaeal thread filament

Nature Communications, 2022
Pili are filamentous appendages on the surface of bacteria and archaea, and play roles in multiple processes such as adhesion, motility and horizontal gene transfer. Here, Gaines et al. describe the structure of a new type of pilus, termed ‘thread’, from
Matthew C. Gaines, Michail N. Isupov, Shamphavi Sivabalasarma, Risat Ul Haque, Mathew McLaren, Clara L. Mollat, Patrick Tripp, Alexander Neuhaus, Vicki A. M. Gold, Sonja-Verena Albers, Bertram Daum   +10 more
doaj   +1 more source

Genomic diversity, lifestyles and evolutionary origins of DPANN archaea

FEMS Microbiology Letters, 2019
Archaea-a primary domain of life besides Bacteria-have for a long time been regarded as peculiar organisms that play marginal roles in biogeochemical cycles.
Nina Dombrowski, Jun-Hoe Lee, T. Williams, P. Offre, A. Spang   +4 more
semanticscholar   +1 more source