Results 61 to 70 of about 175,856 (292)

Direct Synthesis of High‐Valence Protein@UiO‐66 Composites: Linking Crystallization Pathways to Protein Encapsulation

Advanced Materials, EarlyView.
This work reports a direct, biocompatible method to synthesize UiO‐66, enabling one‐step encapsulation of proteins without compromising crystallinity or activity. Using advanced in situ and ex situ techniques, the study reveals that proteins integrate concurrently with MOF growth, forming crystalline protein@UiO‐66 nanoparticles, and provide insight ...
Jesús Cases Díaz, Jana Glatz, Elisa Merced Olivas, Ramon Pons, Joseph P. Patterson, Mónica Giménez‐Marqués   +5 more
wiley   +1 more source

CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection

Nature Communications, 2019
The S-layer is a proteinaceous envelope often found in bacterial and archaeal cells. Here, the authors use CRISPR-based technology to silence slaB, encoding the S-layer membrane anchor, to show that an intact S-layer is important for cell division and ...
Isabelle Anna Zink, Kevin Pfeifer, Erika Wimmer, Uwe B. Sleytr, Bernhard Schuster, Christa Schleper   +5 more
doaj   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Cran1, member of a new class of OLD family ATPases, functions in cell cycle progression in an archaeon

EMBO Reports
Overcoming lysogenization defect (OLD) proteins are diverse ATPase-nucleases functioning in antiphage defense in bacteria. However, the role of these proteins in archaea is currently unknown.
Yunfeng Yang, Shikuan Liang, Junfeng Liu, Xiaofei Fu, Pengju Wu, Haodun Li, Jinfeng Ni, Qunxin She, Mart Krupovic, Yulong Shen   +9 more
doaj   +1 more source

Heavily Armed Ancestors: CRISPR Immunity and Applications in Archaea with a Comparative Analysis of CRISPR Types in Sulfolobales

Biomolecules, 2020
Prokaryotes are constantly coping with attacks by viruses in their natural environments and therefore have evolved an impressive array of defense systems.
Isabelle Anna Zink, Erika Wimmer, Christa Schleper   +2 more
doaj   +1 more source

Archaea in Symbioses [PDF]

Archaea, 2012
During the last few years, the analysis of microbial diversity in various habitats greatly increased our knowledge on the kingdom Archaea. At the same time, we became aware of the multiple ways in which Archaea may interact with each other and with organisms of other kingdoms.
Wrede, Christoph, Dreier, Anne, Kokoschka, Sebastian, Hoppert, Michael   +3 more
openaire   +4 more sources

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Microbial diversity in deep-sea methane seep sediments presented by SSU rRNA gene tag sequencing [PDF]

, 2012
http://www.godac.jamstec.go.jp/darwin/cruise/yokosuka/yk06-03/
ASHI, Juichiro, HIRAI, Miho, IMACHI, Hiroyuki, KAZAMA, Hiromi, NUNOURA, Takuro, TAKAI, Ken, TAKAKI, Yoshihiro, 井町, 寛之, 布浦, 拓郎, 平井, 美穂, 芦, 寿一郎, 風間, 宏美, 高井, 研, 高木, 善弘   +13 more
core   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source