Results 51 to 60 of about 175,856 (292)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery

open access: yeseLife, 2017
The archaellum is the macromolecular machinery that Archaea use for propulsion or surface adhesion, enabling them to proliferate and invade new territories.
Bertram Daum   +7 more
doaj   +1 more source

Analysis of Cell–Cell Bridges in Haloferax volcanii Using Electron Cryo-Tomography Reveal a Continuous Cytoplasm and S-Layer

open access: yesFrontiers in Microbiology, 2021
Halophilic archaea have been proposed to exchange DNA and proteins using a fusion-based mating mechanism. Scanning electron microscopy previously suggested that mating involves an intermediate state, where cells are connected by an intercellular bridge ...
Shamphavi Sivabalasarma   +7 more
doaj   +1 more source

Protein acetylation in archaea, bacteria, and eukaryotes [PDF]

open access: yes, 2010
Proteins can be acetylated at the alpha-amino group of the N-terminal amino acid (methionine or the penultimate amino acid after methionine removal) or at the epsilon-amino group of internal lysines.
Lainio, Jarmo   +1 more
core  

Correlating microbial community profiles with geochemical data in highly stratified sediments from the Arctic Mid-Ocean Ridge [PDF]

open access: yes, 2012
Microbial communities and their associated metabolic activity in marine sediments have a profound impact on global biogeochemical cycles. Their composition and structure are attributed to geochemical and physical factors, but finding direct correlations ...
Baumberger, Tamara   +10 more
core   +1 more source

Taxis in archaea [PDF]

open access: yesEmerging Topics in Life Sciences, 2018
Microorganisms can move towards favorable growth conditions as a response to environmental stimuli. This process requires a motility structure and a system to direct the movement. For swimming motility, archaea employ a rotating filament, the archaellum.
Tessa E.F. Quax   +2 more
openaire   +4 more sources

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Minimal ATP‐Independent N2‐Reducing Systems Defined by L‐Cluster‐Bound Nitrogenase Assembly Platforms

open access: yesAngewandte Chemie, EarlyView.
Association of the L‐cluster with the nitrogenase assembly proteins NifEN (NifENL) or NifB (NifBL) intrinsically endows these proteins with N2‐reducing activity, enabling in vitro N2‐reduction by NifENL and NifBL when supplied with chemical reductants or photoexcited quantum dots while supporting in vivo N2‐fixation in NifENL‐ and NifENL‐expressing ...
Robert Quechol   +4 more
wiley   +2 more sources

ADP-dependent Phosphofructokinases in Mesophilic and Thermophilic Methanogenic Archaea [PDF]

open access: yes, 2001
Phosphofructokinase (PFK) is a key enzyme of the glycolytic pathway in all domains of life. Two related PFKs, ATP-dependent and PPi-dependent PFK, have been distinguished in bacteria and eucarya, as well as in some archaea.
Verhees, C.H.   +5 more
core   +1 more source

Osmoadaptation in Archaea [PDF]

open access: yesApplied and Environmental Microbiology, 1999
The ability to adapt to fluctuations in external osmotic pressure (osmoadaptation) and the development of specific mechanisms to achieve this (osmoregulation) are fundamental to the survival of cells ([6][1], [16][2], [67][3], [73][4], [76][5]).
, Martin, , Ciulla, , Roberts
openaire   +2 more sources

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