Results 111 to 120 of about 518 (150)

Simplified Admix Archaeal Glycolipid Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Enhances Protection from Murine Melanoma. [PDF]

Biomedicines, 2019
Stark FC, Agbayani G, Sandhu JK, Akache B, McPherson C, Deschatelets L, Dudani R, Hewitt M, Jia Y, Krishnan L, McCluskie MJ.   +10 more
europepmc   +1 more source

Effect of Different Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins. [PDF]

Vaccines (Basel), 2019
Akache B, Deschatelets L, Harrison BA, Dudani R, Stark FC, Jia Y, Landi A, Law JLM, Logan M, Hockman D, Kundu J, Tyrrell DL, Krishnan L, Houghton M, McCluskie MJ.   +14 more
europepmc   +1 more source

Nanoarchaeosomes for synergistic photochemotherapy in triple-negative breast cancer. [PDF]

Sci Rep
Basha SS, Thomas S, Ariraman S, Babu RS, Santhosh PB, Stoychev L, Genova J, Daskalova A, Bhoir B, Selvaraj V, Sudhakar S.   +10 more
europepmc   +1 more source

A Comparative Review of Tocosomes, Liposomes, and Nanoliposomes as Potent and Novel Nanonutraceutical Delivery Systems for Health and Biomedical Applications. [PDF]

Biomedicines
Atrooz O, Kerdari E, Mozafari MR, Reihani N, Asadi A, Torkaman S, Alavi M, Taghavi E.   +7 more
europepmc   +1 more source

Phytocannabinoids: Exploring Pharmacological Profiles and Their Impact on Therapeutical Use. [PDF]

Int J Mol Sci
Blebea NM, Pricopie AI, Vlad RA, Hancu G.   +3 more
europepmc   +1 more source

Archaeosomes Facilitate Storage and Oral Delivery of Cannabidiol [PDF]

International Journal of Pharmaceutics, 2023
Cannabidiol (CBD) has received great scientific interest due to its numerous therapeutic applications. Degradation in the gastrointestinal (GI) tract, first-pass metabolism, and low water solubility restrain bioavailability of CBD to only 6% in current oral administration. Lipid-based nanocarriers are delivery systems that may enhance accessibility and
Julian Quehenberger, Oliver Spadiut
exaly   +4 more sources

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Archaeosomes as Adjuvants for Combination Vaccines

Journal of Liposome Research, 2004
The present study evaluated the potential of archaesomes, prepared from the total polar lipids extracted from Methanobrevibacter smithii, as adjuvants for combination (multivalent) vaccines. Groups of Balb/c mice were immunized subcutaneously at day 0 and 21 with one of the following vaccines: trivalent vaccine formulated by the simultaneous co ...
Wangxue Chen, Rhonda Kuolee, Girishchandra B Patel   +2 more
exaly   +3 more sources

Short-Term Repeated-Dose Toxicity Profile of Archaeosomes Administered to Mice via Intravenous and Oral Routes

International Journal of Toxicology, 2003
Archaeosomes, liposomes made from polar ether lipids of archaea, show promise for vaccine and drug delivery applications. The potential toxicity of intravenously (14, 70, or 140 mg/kg/day for 5 consecutive days) and orally (gavaged at 55, 275, or 550 mg ...
Abdelwahab Omri, Girishchandra B Patel
exaly   +2 more sources

Investigation of Archaeosomes as Carriers for Oral Delivery of Peptides

Biochemical and Biophysical Research Communications, 2010
Oral administration of peptide and protein drugs faces a big challenge partly due to the hostile gastrointestinal (GI) environment. Lipid-based delivery systems are attractive because they offer some protection for peptides and proteins. In this context, we prepared a special lipid-based oral delivery system: archaeosomes, made of the polar lipid ...
Yuhong Xu
exaly   +3 more sources

Archaeosomes With Encapsulated Antigens for Oral Vaccine Delivery

Vaccine, 2011
Traditional phosphodiester lipid vesicles (liposomes) are not stable and could be easily degraded in the gastrointestinal (GI) tract. We prepared a novel lipid based oral delivery system: archaeosomes, made of the polar lipid fraction E (PLFE) extracted from Sulfolobus acidocaldarius, and tested their immunogenic potentials as oral vaccine delivery ...
Yuhong Xu, Lihui Zhang
exaly   +3 more sources